New statistical method improves genomic analyses

A new statistical method provides a more efficient way to uncover biologically meaningful changes in genomic data that span multiple conditions—such as cell types or tissues.

Making lab-grown brain organoids 'brainier'

By using stem cells to grow miniature brain-like organs in the lab, scientists have opened a new avenue for studies of neurological development, disease and therapies that can't be conducted in living people. But not all ...

How to find marker genes in cell clusters

Which genes are specific for a certain cell type, i.e., "mark" their identity? With the increasing size of datasets nowadays, answering this question is often challenging. Often, marker genes are simply genes that have been ...

New data analysis tool uncovers important COVID-19 clues

A new data analysis tool developed by Yale researchers has revealed the specific immune cell types associated with increased risk of death from COVID-19, they report Feb. 28 in the journal Nature Biotechnology.

How a COVID-19 infection changes blood cells in the long run

Using real-time deformability cytometry, researchers at the Max-Planck-Zentrum für Physik und Medizin in Erlangen were able to show for the first time: COVID-19 significantly changes the size and stiffness of red and white ...

Researchers visualize over 10,000 proteins of fruit flies

The human genome codes for more than 20,000 different proteins, however the molecular role for many of these proteins is not known. As most proteins are conserved from fly to humans, understanding the molecular role of a ...

Are embryonic stem cells and artificial stem cells equivalent?

Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General Hospital and Harvard Medical School have found new evidence suggesting some human induced pluripotent stem cells are the 'functional equivalent' of human ...

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