The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications ...
Cell & Microbiology
Jun 15, 2022
0
136
Using specialized nanoparticles, MIT engineers have developed a way to turn off specific genes in cells of the bone marrow, which play an important role in producing blood cells. These particles could be tailored to help ...
Bio & Medicine
Oct 5, 2020
0
597
Bone marrow transplants, also known as hematopoietic stem cell transplants, are life-saving treatments for aggressive diseases, such as leukemia and multiple myeloma, and infections such as HIV. The procedure entails infusion ...
Biotechnology
Feb 11, 2019
0
177
A microbial sensor that helps identify and fight bacterial infections also plays a key role in the development of blood stem cells, providing a valuable new insight in the effort to create patient-derived blood stem cells ...
Cell & Microbiology
Dec 19, 2023
0
96
A team of bioengineers and biomedical scientists from the University of Sydney and the Children's Medical Research Institute (CMRI) at Westmead have used 3D photolithographic printing to create a complex environment for assembling ...
Biotechnology
Aug 11, 2023
0
362
In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept ...
Biotechnology
Jul 27, 2023
0
69
Blood-forming stem cells found in bone marrow are the life-saving component used in bone marrow transplants. However, suitable donors cannot be found in many cases. A new study reveals how the human embryo develops the precursor ...
Cell & Microbiology
Apr 28, 2022
0
67
Scientists have found a way to prove that biochemical signals sent from cell to cell play an important role in determining how those cells develop.
Cell & Microbiology
Dec 23, 2021
0
166
Researchers at the Center for Genomic Regulation (CRG) in Barcelona and Columbia University in New York City have identified a protein that is critical for the expansion of typically scarce, life-saving blood stem cells.
Cell & Microbiology
Dec 8, 2020
0
332
Blood diseases such as leukemia and lymphoma are currently treated with bone marrow transplants—a transfer of blood stem cells from a healthy person to a patient in need. But the demand for patient-matched blood stem cells ...
Cell & Microbiology
May 20, 2019
0
196
