For more than 40 years, scientists have hypothesized the existence of enzyme clusters, or "metabolons," in facilitating various processes within cells. Using a novel imaging technology combined with mass spectrometry, researchers ...
Biochemistry
Apr 16, 2020
0
402
Glycosylation—the attachment of sugars to proteins—plays a critical role in both cellular function and in the development of therapeutics, like vaccines.
Cell & Microbiology
Nov 27, 2019
0
57
In order to meet the demands of growing human populations, agricultural production must double within the next 30 years. Yet the health of today's crops and the promise of their yield face a rising slate of threats—from ...
Plants & Animals
Sep 19, 2019
0
55
Microbes are well-known among biologists as master engineers of useful small molecules, and there are many tricks of their trade. When researchers at the University of Illinois took a closer look at how a known microbe makes ...
Biochemistry
Sep 5, 2019
0
60
Mycophenolic acid (MPA), discovered in 1893, was the first natural antibiotic to be isolated and crystallized in human history. Today, this fungal metabolite has been developed into multiple first-line immunosuppressive drugs ...
Biochemistry
Jun 21, 2019
1
1
Scientists have discovered a new chemical process—also known as a biosynthetic pathway—in bacteria which could lead to a new generation of antibiotics being produced and manufactured.
Biochemistry
Nov 26, 2018
0
145
Chemists scouring Appalachia for exotic microorganisms that could yield blockbuster drugs have reported a unique find from the smoldering remains of a coal mine fire that's burned for nearly a decade in southeastern Kentucky.
Biochemistry
Feb 6, 2017
0
22
Fungal infections can be devastating to human health, killing approximately 150 people every hour, resulting in over a million deaths every year, more than malaria and tuberculosis combined.
Cell & Microbiology
Jun 14, 2016
0
97
The fungus Aspergillus fumigatus produces a group of previously unknown natural products. With reference to plant isoquinoline alkaloids, these substances have been named fumisoquins. Researchers from Jena (Germany) discovered ...
Biotechnology
May 27, 2016
0
7
Infections with American foulbrood can destroy entire bee populations. A team of German and Dutch researchers has now isolated metabolic products of the pathogen that causes it, Paenibacillus larvae. The structures of the ...
Biochemistry
Aug 1, 2014
0
0
