A rapid, easy-to-use DNA amplification method at 37 Celcius

Scientists in Japan have developed a way of amplifying DNA on a scale suitable for use in the emerging fields of DNA-based computing and molecular robotics. By enabling highly sensitive nucleic acid detection, their method ...

How to develop affordable sensors using slime mold

Physarum polycephalum, which literally means "many-headed slime," is a slime mold that inhabits damp and dark habitats, such as decaying wood. Thanks to its ability to respond to stimuli such as light, chemicals and vibrations, ...

Sweating the small stuff

Assistant professor of medical engineering Wei Gao is enriching the field of personalized and precision medicine with an abundant source of chemical data: sweat.

Wristbands do a health check while you work out

Next-generation fitness sensors could give deeper insights into human health through noninvasive testing of bodily fluids. A stretchy patch developed at KAUST could help this approach by making it easier to analyze sweat ...

Biosensor 'bandage' collects and analyzes sweat

Like other biofluids, sweat contains a wealth of information about what's going on inside the body. However, collecting the fluid for analysis, usually by dripping or absorbing it from the skin's surface, can be time-consuming ...

Directed evolution builds nanoparticles

The 2018 Nobel Prize in Chemistry went to three scientists who developed the method that forever changed protein engineering: directed evolution. Mimicking natural evolution, directed evolution guides the synthesis of proteins ...

Researchers develop diagnostic tool for detecting cryptosporidium

A handheld 'tricorder' that can test for biological contamination in real-time has been the dream of science fiction fans for decades. And UBC Okanagan engineers say the technology is closer to science fact than ever before.

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A biosensor is a device for the detection of an analyte that combines a biological component with a physicochemical detector component.

It consists of 3 parts:

The most widespread example of a commercial biosensor is the blood glucose biosensor, which uses the enzyme glucose oxidase to break blood glucose down. In doing so it first oxidizes glucose and uses two electrons to reduce the FAD (a component of the enzyme) to FADH2. This in turn is oxidized by the electrode (accepting two electrons from the electrode) in a number of steps. The resulting current is a measure of the concentration of glucose. In this case, the electrode is the transducer and the enzyme is the biologically active component.

Recently, arrays of many different detector molecules have been applied in so called electronic nose devices, where the pattern of response from the detectors is used to fingerprint a substance. Current commercial electronic noses, however, do not use biological elements.

A canary in a cage, as used by miners to warn of gas could be considered a biosensor. Many of today's biosensor applications are similar, in that they use organisms which respond to toxic substances at a much lower level than us to warn us of their presence. Such devices can be used in environmental monitoring, trace gas detection and in water treatment facilities.

This text uses material from Wikipedia, licensed under CC BY-SA