Computational 'match game' identifies potential antibiotics

Computational biologists at Carnegie Mellon University have devised a software tool that can play a high-speed "Match Game" to identify bioactive molecules and the microbial genes that produce them so they can be evaluated ...

'Pick 'n' Mix' chemistry to grow cultures of bioactive molecules

Chemists at ETH-Zürich and ITbM, Nagoya University have developed a new method to build large libraries of bioactive molecules – which can be used directly for biological assays – by simply mixing a small number of building ...

Precise docking sites for cells

The Petri dish is a classical biological laboratory device, but it is no ideal living environment for many types of cells. Studies lose validity, as cell behavior on a flat plastic surface differs from that in branched lung ...

Approaching an ideal amino acid synthesis using hydrogen

Osaka University researchers demonstrated a reductive alkylation method for the functionalization of substituted amines using hydrogen, which is efficiently catalyzed by innocuous main-group catalysts. Their reaction generated ...

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