Epigenetic 'switch' regulates RNA-protein interactions

Chemical changes - also known as epigenetic modifications - to messenger RNA (mRNA) are thought to play an important role in gene expression, and have recently been found to affect biological processes such as circadian clock ...

X-rays show how flu antibody binds to viruses

An important study conducted in part at the Department of Energy's SLAC National Accelerator Laboratory may lead to new, more effective vaccines and medicines by revealing detailed information about how a flu antibody binds ...

Excitonic dark states shed light on TMDC atomic layers

(Phys.org) —A team of Berkeley Lab researchers believes it has uncovered the secret behind the unusual optoelectronic properties of single atomic layers of transition metal dichalcogenide (TMDC) materials, the two-dimensional ...

How do protein binding sites stay dry in water?

In a report to be published soon in EPJE¹, researchers from the National University of the South in Bahía Blanca, Argentina studied the condition for model cavity and tunnel structures resembling the binding sites ...

Study reveals the multitasking secrets of an RNA-binding protein

Researchers from Princeton University and the National Institute of Environmental Health Sciences have discovered how a fruit fly protein binds and regulates two different types of RNA target sequence. The study, which will ...

Scientists shine light on protein linked to fat storage

In new research that may have implications for strategies fighting obesity and diabetes, UNSW scientists have uncovered the structure of a protein believed to regulate the formation of fat in cells, as well as the formation ...

Biologists reveal novel drug binding site in NMDA receptor subunit

Structural biologists at Cold Spring Harbor Laboratory (CSHL) have obtained a precise molecular map of the binding site for an allosteric inhibitor in a subtype of the NMDA (N-methyl-D-aspartate) receptor, which is commonly ...

Researchers slash pre-drug screening time from years to days

Researchers at Ben-Gurion University of the Negev (BGU) and The Hebrew University of Jerusalem (HU) have developed a powerful tool that will streamline and accelerate the development of disease therapies, transforming a multi-year ...

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