An episode of major depression can be crippling, impairing the ability to sleep, work, or eat. In severe cases, the mood disorder can lead to suicide. But the drugs available to treat depression, which can affect one in six ...
Biochemistry
Jul 28, 2016
0
716
A collaborative effort by cancer researchers at Cold Spring Harbor Laboratory (CSHL) and chemists at Boehringer Ingelheim (BI), a pharmaceutical firm, has resulted in the identification of a new drug target in leukemia and ...
Biochemistry
Jul 5, 2016
0
77
Researchers at Karolinska Institutet in Sweden have taken a step closer to understanding the mechanism that leads to the fusion of egg and sperm at fertilisation. Using the technique X-ray crystallography, they have determined ...
Cell & Microbiology
Feb 8, 2016
1
7
A group of scientists at the University of Amsterdam (UvA) has developed a new approach in enhancing catalytic performance. In the current issue of Nature Chemistry they present functionalised, self-assembled nanospheres ...
Materials Science
Jan 13, 2016
0
10
Inside the cell, DNA is tightly coiled and packed with several proteins into a structure called "chromatin", which allows DNA to fit in the cell while also preventing genes from being expressed at the wrong time. Guided by ...
Biochemistry
Jun 18, 2015
0
181
Remo Rohs is looking for some deep connections. He is integrating genomics and structural biology to uncover some significant insights into how proteins recognize DNA.
Cell & Microbiology
Apr 3, 2015
1
71
(Phys.org)—In the complex, somewhat rarified world of interactions between various flavors of RNA, one elusive goal is to understand the precise regulatory relationships between competing endogenous RNA (ceRNA), microRNA ...
An important study conducted in part at the Department of Energy's SLAC National Accelerator Laboratory may lead to new, more effective vaccines and medicines by revealing detailed information about how a flu antibody binds ...
Biochemistry
Dec 9, 2014
0
0
(Phys.org) —Cholera against cholera: a novel inhibitor prevents the cholera toxin from binding to carbohydrates found on the surface of intestinal cells. An international team of researchers has described their elegant ...
Biochemistry
Jul 4, 2014
0
0
Transcription factor (TF) proteins switch particular genes on and off by homing in on specific sequences of nucleotides scattered throughout the genome. In some cases, this regulation is a team effort, where pairs of TFs—or ...
Biotechnology
Nov 20, 2013
0
0
