According to researchers at the University of Illinois Chicago, the antibiotics used to treat common bacterial infections, like pneumonia and sinusitis, may also be used to treat human diseases, like cancer. Theoretically, ...
Cell & Microbiology
May 25, 2021
0
36
Sarecycline, a drug approved for use in the United States in 2018, is the first new antibiotic approved to treat acne in more than 40 years. Now, researchers at Yale and the University of Illinois-Chicago have discovered ...
Biochemistry
Aug 3, 2020
0
27
A team of scientists from Scripps Research and Stanford University has recorded in real time a key step in the assembly of ribosomes—the complex and evolutionarily ancient "molecular machines" that make proteins in cells ...
Cell & Microbiology
Nov 22, 2019
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3733
Bacterial ribosomes need a single-stranded ribosome binding site (RBS) to initiate protein synthesis, whereas stable RNA structure blocks initiation. Paradoxically, structured mRNAs can nevertheless be efficiently translated. ...
Cell & Microbiology
Jul 15, 2019
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229
Groundbreaking research at the new long-wavelength macromolecular crystallography beamline (I23) at Diamond Light Source has for the first time demonstrated the location of potassium ions in bacterial ribosomes. Ribosomes ...
Biochemistry
Jun 7, 2019
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163
Antibiotics have been a pillar of modern medicine since the 1940s. Streptomycin, which belongs to a class of antibiotics called aminoglycosides, was the first hint of light in the millennia-long search for a treatment for ...
Cell & Microbiology
Aug 7, 2018
0
84
Research from the University of Illinois at Chicago suggests bond duration, not bond tightness, may be the most important differentiator between antibiotics that kill bacteria and antibiotics that only stop bacterial growth.
Biochemistry
Dec 12, 2017
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27
Ludwig Maximilian University of Munich researchers have elucidated a mechanism that recycles bacterial ribosomes stalled on messenger RNAs that lack termination codons. The protein involved provides a potential target for ...
Cell & Microbiology
Dec 5, 2016
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7
Spores of Bacillus bacteria can survive for years in a dormant state, and then germinate in minutes. But it has long been unclear whether germination required protein synthesis, or cellular energy packets, which are known ...
Cell & Microbiology
Sep 20, 2016
0
4
Microbes that can reproduce rapidly in times of plenty have an evolutionary stockpile of extra genes that allows them to quickly respond to changing conditions such as oil spills or outbreaks of intestinal diseases.
Cell & Microbiology
Sep 12, 2016
0
16
