Related topics: bacteria · antibiotics · immune cells · pneumonia · infection

How bugs overcome host defenses

Bacterial pathogens must acquire nutrient metals from the host to survive and cause disease. To counter infection, hosts attempt to starve bacteria by hiding metals away in a process called "nutritional immunity." Bacteria ...

Multi-drug resistant UTIs—is the answer in our food?

Urinary tract infections (UTIs) are among the world's most common bacterial infections, affecting around 50 per cent of women and five per cent of men. They can present as low-level cystitis or cause debilitating and potentially ...

Organoids reveal inflammatory processes in chlamydia infections

For a long time, researchers were only able to examine human cells infected with bacteria by using cancer cell lines. However, these transformed cells often give a false impression of the infection process. Fallopian tube ...

Analysis reveals key gene for bacterial infection

To successfully infect their hosts, bacteria need to evade the host immune system in order to reproduce and spread. Over the course of evolution, hosts—such as humans—develop increasingly sophisticated defenses against ...

Diabetes impairs multipotent stromal cell antibacterial activity

A new study reveals that the multipotent stromal cells (MSCs) of persons with diabetes have diminished capacity to fight off bacterial infection, providing new understanding into the basis of diabetes-associated immune dysfunction. ...

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Infection

An infection is the detrimental colonization of a host organism by a foreign species. In an infection, the infecting organism seeks to utilize the host's resources to multiply, usually at the expense of the host. The infecting organism, or pathogen, interferes with the normal functioning of the host and can lead to chronic wounds, gangrene, loss of an infected limb, and even death. The host's response to infection is inflammation. Colloquially, a pathogen is usually considered a microscopic organism though the definition is broader, including parasites, fungi, viruses, prions, and viroids. A symbiosis between parasite and host, whereby the relationship is beneficial for the former but detrimental to the latter, is characterised as parasitism. The branch of medicine that focuses on infections and pathogens is infectious disease. "When infection attacks the body, anti-infective drugs can help turn the tide of battle. Four types of anti-infective drugs exist: antibacterial, antiviral, antitubercular, and antifungal. A secondary infection is an infection that occurs during or following treatment of another already existing primary infection.

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