Cell death, a life-giving event, can also trigger severe disease
When the body machinery that kills off hundreds of millions of cells a day fails, inflammation and sickness are often not far behind.
When the body machinery that kills off hundreds of millions of cells a day fails, inflammation and sickness are often not far behind.
Cell & Microbiology
Mar 21, 2023
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Rheumatoid arthritis (RA), known as "immortal cancer," is a chronic, progressive autoimmune inflammatory disease. The development and application of an RA high-sensitivity theranostics probe can help to accurately monitor ...
Bio & Medicine
Feb 10, 2023
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217
Messenger RNAs (mRNAs) contain chemical marks that are critical for antiviral defense in cells, according to a new study from researchers at Weill Cornell Medicine. The finding solves a 50-year mystery concerning the purpose ...
Cell & Microbiology
Feb 2, 2023
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63
University of Queensland researchers have identified a pathway in cells that could be used to reprogram the body's immune system to fight back against both chronic inflammatory and infectious diseases.
Cell & Microbiology
Jan 18, 2023
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276
Scientists at Scripps Research have reported success in initial tests of a new, nanotech-based strategy against autoimmune diseases.
Bio & Medicine
Dec 1, 2022
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341
The high level of reactive oxygen species (ROS) in the rheumatoid arthritis (RA) microenvironment and its persistent inflammatory nature can promote damage to joints, bones, and the synovium. Strategies that integrate effective ...
Bio & Medicine
Oct 21, 2022
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Proteins are like machines. For some diseases, it can be useful to turn these machine off or on when they are too active or not active enough. One way to control switching in a protein, such as a nuclear receptor, is to put ...
Molecular & Computational biology
Jun 1, 2022
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5
DNA methylation is a major epigenetic modification that is crucial for mammalian development. For instance, DNA methylation is central to inexhaustible biological processes, such as gene regulation and cell fate decisions. ...
Cell & Microbiology
Apr 18, 2022
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Otis was our bighearted bloodhound, whom we loved dearly. He had an active life playing with our three other dogs and going for long walks every morning and evening with us. But when he was eight years old, his lifestyle ...
Veterinary medicine
Mar 16, 2022
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15
Fourteen percent of Aspergillus fumigatus isolates cultured from garden soils were resistant to an agricultural triazole antifungal drug, tebuconazole. Tebuconazole resistance confers resistance to medical triazoles that ...
Cell & Microbiology
Jan 13, 2022
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Arthritis (from Greek arthro-, joint + -itis, inflammation; plural: arthritides) is a group of conditions involving damage to the joints of the body.
There are different forms of arthritis and each has a different cause. The most common form of arthritis, osteoarthritis (degenerative joint disease) is a result of trauma to the joint, infection of the joint, or age. Other arthritis forms are rheumatoid arthritis and psoriatic arthritis, autoimmune diseases in which the body attacks itself. Septic arthritis is caused by joint infection. Gouty arthritis is caused by deposition of uric acid crystals in the joint, causing inflammation. There is also an uncommon form of gout caused by the formation of rhomboid crystals of calcium pyrophosphate. This gout is known as pseudogout.
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