Malaria's secret to surviving in the blood uncovered
New research from the Francis Crick Institute has found how the malaria parasite protects itself from toxic compounds in red blood cells.
New research from the Francis Crick Institute has found how the malaria parasite protects itself from toxic compounds in red blood cells.
Biochemistry
Jun 30, 2020
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275
Drug delivery systems (DDSs) control the dosage and timing of drugs. Numerous DDS studies have been conducted, but most have focused on treatments for cancer. New research from Kumamoto University uses a DDS to treat malaria.
Bio & Medicine
Mar 26, 2018
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22
The first three-dimensional image capturing a critical malaria 'conductor' protein could lead to the development of a new class of antimalarial drugs.
Cell & Microbiology
Jul 27, 2015
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34
The iron-containing molecule heme is necessary for life. Cells require heme to perform the chemical reactions that produce energy, among other critical tasks.
Cell & Microbiology
Feb 27, 2017
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10
The global effect of malaria is devastating. In 2020, there were more than 240 million cases and over 600,000 deaths, mostly in lower income countries in Africa. The most vulnerable are children under the age of five.
Molecular & Computational biology
Aug 12, 2022
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33
Significant headway has been made in controlling malaria. However, two vexing problems remain: currently available treatments are unable to block transmission of the parasite that causes the disease, and the parasite often ...
Cell & Microbiology
Sep 6, 2017
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43
Scientists identify 3D structure of enzyme critical to the creation of anticancer and antimalarial compounds in plants
Biochemistry
Nov 9, 2015
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13
Much of common pharmaceutical development today is the product of laborious cycles of tweaking and optimization. In each drug, a carefully concocted formula of natural and synthetic enzymes and ingredients works together ...
Molecular & Computational biology
Apr 21, 2021
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55
Melbourne researchers are homing in on a new target for malaria treatment, after developing a compound that blocks the action of a key 'gatekeeper' enzyme essential for malaria parasite survival.
Cell & Microbiology
Jul 1, 2014
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0
Jigang Wang and colleagues have made significant progress in unraveling the antimalarial mechanisms of artemisinin (ART) and its derivatives. Their latest research, published in the journal Engineering, sheds light on the ...
Cell & Microbiology
Sep 21, 2023
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43