Taking aim at a key malaria molecule
The iron-containing molecule heme is necessary for life. Cells require heme to perform the chemical reactions that produce energy, among other critical tasks.
The iron-containing molecule heme is necessary for life. Cells require heme to perform the chemical reactions that produce energy, among other critical tasks.
Cell & Microbiology
Feb 27, 2017
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The first three-dimensional image capturing a critical malaria 'conductor' protein could lead to the development of a new class of antimalarial drugs.
Cell & Microbiology
Jul 27, 2015
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Melbourne researchers are homing in on a new target for malaria treatment, after developing a compound that blocks the action of a key 'gatekeeper' enzyme essential for malaria parasite survival.
Cell & Microbiology
Jul 1, 2014
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Highlighting an important but unexplored area of evolution, scientists at The Scripps Research Institute (TSRI) have found evidence that, over hundreds of millions of years, an essential protein has evolved chiefly by changing ...
Cell & Microbiology
Sep 29, 2013
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A biology lab at Washington University has just cracked the structure and function of a protein that plays a key role in the life of a parasite that killed 655,000 people in 2010.
Biochemistry
Jan 6, 2012
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Snug inside a human red blood cell, the malaria parasite hides from the immune system and fuels its growth by digesting hemoglobin, the cell's main protein. The parasite, however, must obtain additional nutrients from the ...
Biotechnology
May 26, 2011
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Researchers have found that the anti-malarial drug quinine can block a cell's ability to take up the essential amino acid tryptophan, a discovery that may explain many of the adverse side-effects associated with quinine. ...
Biochemistry
Jun 26, 2009
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A new study, published on May 25, 2023 in Frontiers in Plant Science by researchers at the Royal Botanic Gardens, Kew and partners, has identified that the use of machine learning could speed up the search for plants with ...
Plants & Animals
May 25, 2023
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A team of researchers from the Singapore University of Technology and Design (SUTD) and Nanyang Technological University (NTU) have developed novel ferrocene-based molecules that impair the malaria parasite's metabolic function ...
Biochemistry
Dec 20, 2018
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Scientists identify 3D structure of enzyme critical to the creation of anticancer and antimalarial compounds in plants
Biochemistry
Nov 9, 2015
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