Researchers at Yale University, New Haven, have optimized a polymer-based mRNA vehicle for targeted lung delivery and demonstrated the potential of the platform for mucosal vaccination against respiratory pathogens.
Most cells evolve slowly, accumulating incremental changes that better suit their environments. Immune cells, because they must adapt rapidly to counter new threats, evolve much more quickly. Part of that, UCLA physicists ...
Evolution
Apr 13, 2023
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267
Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading. Multiple therapeutic cancer vaccines are being ...
Bio & Medicine
Mar 15, 2024
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8
Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have proposed a new "nano-micro composite" delivery concept for vaccines.
Bio & Medicine
Dec 13, 2023
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54
To ensure that vaccines provide strong and lasting immunization, it is often necessary to supplement the actual vaccine (antigen) with additives that stimulate the immune system: adjuvants. Today, only a few substances have ...
Biochemistry
Nov 30, 2023
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1
The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus ...
Bio & Medicine
Apr 3, 2024
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18
Francis Crick Institute scientists have discovered that immune cells called B cells use mechanical forces to physically pull antigens such as viruses or toxins from the surfaces of other cells.
Cell & Microbiology
Jan 12, 2017
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6
Leiden researchers have carried out successful tests using a new method of packaging a cancer vaccine in nanoparticles. The new vaccine has induced a strong immune reaction in mice. The researchers believe that this method ...
Bio & Medicine
Feb 23, 2016
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28
Messenger RNA (mRNA) vaccines are revolutionizing the therapy of cancer. They can be flexibly developed in a short period of time, allowing transient expression of multiple antigens for safe and efficient immunization. A ...
Bio & Medicine
Oct 16, 2023
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