Tiny DNA reader to advance development of anticancer drugs
DNA is small. Really, really, small. So, when researchers want to study the structure of a single-stranded DNA, they can't just pull out their microscopes: they have to get creative.
DNA is small. Really, really, small. So, when researchers want to study the structure of a single-stranded DNA, they can't just pull out their microscopes: they have to get creative.
Biotechnology
Mar 7, 2019
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6
Much like shoelaces or dangly necklaces, DNA strands can tangle up in unruly knots. Specialized enzymes keep DNA organized when cells divide, so the cells split smoothly and don't get stuck. But in tumor cells, this failsafe ...
Biochemistry
Feb 5, 2019
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8
Sanguinarine is a natural product, a chemical made by certain plants including the bloodroot plant (Sanguinaria canadensis), the Mexican prickly poppy (Argemone mexicana), Chelidonium majus, and Macleaya cordata. It is a ...
Bio & Medicine
Nov 2, 2018
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37
Cancer-fighting drugs used on humans can help plants fight disease as well. That discovery, by two Washington State University plant pathologists, could help scientists develop new pathways for plants to battle infection, ...
Biotechnology
Aug 14, 2018
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28
A new anticancer agent developed by the University of Warwick has been studied using microfocus synchrotron X-ray fluorescence (SXRF) at I18 at Diamond Light Source. As described in the Journal of Inorganic Biochemistry, ...
Biochemistry
Jun 19, 2018
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28
With the goal of minimizing the side effects of chemotherapy on healthy tissues, a team of researchers at the Center for Self-assembly and Complexity, within the Institute for Basic Science (IBS) have developed novel nanocontainers ...
Materials Science
Mar 9, 2018
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42
Following the discovery of a new and very valuable enzyme which folds linear molecules into different shapes, scientists at the John Innes Centre are building a 'triterpene machine' which will enable them to custom-build ...
Biotechnology
Jul 11, 2016
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9
Drug treatments are made more efficient by delivering them to specific sites in the body where they are needed. For example, specific targeting of anticancer drugs to tumour sites could reduce required doses, provide more ...
Bio & Medicine
May 24, 2016
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6
A group of scientists from Moscow universities led by Yan Ivanenkov, the head of Laboratory of Medical Chemistry and Bioinformatics in MIPT, has succeeded in synthesizing a set of novel selenohydantoins with anticancer and ...
Biochemistry
Mar 15, 2016
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44
Scientists identify 3D structure of enzyme critical to the creation of anticancer and antimalarial compounds in plants
Biochemistry
Nov 9, 2015
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13