How E. coli get the power to cause urinary tract infections
Through a quirk of anatomy, women are especially prone to urinary tract infections, with almost half dealing with one at some point in their lives.
Through a quirk of anatomy, women are especially prone to urinary tract infections, with almost half dealing with one at some point in their lives.
Cell & Microbiology
May 3, 2024
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University of Central Florida College of Medicine researcher Renee Fleeman is on a mission to kill drug-resistant bacteria, and her latest study has identified a therapy that can penetrate the slime that such infections use ...
Cell & Microbiology
May 2, 2024
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27
Antibiotic medicines became a popular treatment for bacterial infections in the early 20th century and emerged as a transformational tool in human health. Through the middle of the century, novel antibiotics were regularly ...
Cell & Microbiology
May 1, 2024
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26
Researchers at the University Hospital Bonn (UKB), the University of Bonn, and the German Center for Infection Research (DZIF) have discovered a new lantibiotic, namely epilancin A37. It is produced by staphylococci that ...
Cell & Microbiology
Apr 29, 2024
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23
As Lyme disease cases rise in the U.S., humans are not the only ones at risk. Veterinarians with the Virginia-Maryland College of Veterinary Medicine say dogs are increasingly vulnerable to this tick-borne illness.
Veterinary medicine
Apr 25, 2024
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1
Yale researchers have uncovered new details on how bacteria like E. coli build their protective barriers, which will inform new antibiotic development.
Cell & Microbiology
Apr 22, 2024
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Human history was forever changed with the discovery of antibiotics in 1928. Infectious diseases such as pneumonia, tuberculosis and sepsis were widespread and lethal until penicillin made them treatable. Surgical procedures ...
Cell & Microbiology
Apr 16, 2024
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3
Hydrogels are popular for use in skin ailments and tissue engineering. These polymer-based biocompatible materials are useful for their abilities to retain water, deliver drugs into wounds, and biodegrade. However, they are ...
Biochemistry
Apr 2, 2024
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55
Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice. The new antibiotic class ...
Cell & Microbiology
Apr 1, 2024
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102
The intricacies of how intestinal bacteria adapt to their environment have yet to be fully explored. Researchers from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of California, ...
Cell & Microbiology
Mar 25, 2024
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In common usage, an antibiotic (from the Ancient Greek: ἀντί – anti, "against", and βίος – bios, "life") is a substance or compound that kills bacteria or inhibits their growth. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused by microorganisms, including fungi and protozoa.
The term "antibiotic" was coined by Selman Waksman in 1942 to describe any substance produced by a microorganism that is antagonistic to the growth of other microorganisms in high dilution. This original definition excluded naturally occurring substances that kill bacteria but are not produced by microorganisms (such as gastric juice and hydrogen peroxide) and also excluded synthetic antibacterial compounds such as the sulfonamides. Many antibiotics are relatively small molecules with a molecular weight less than 2000 Da.[citations needed]
With advances in medicinal chemistry, most antibiotics are now semisynthetic—modified chemically from original compounds found in nature, as is the case with beta-lactams (which include the penicillins, produced by fungi in the genus Penicillium, the cephalosporins, and the carbapenems). Some antibiotics are still produced and isolated from living organisms, such as the aminoglycosides, and others have been created through purely synthetic means: the sulfonamides, the quinolones, and the oxazolidinones. In addition to this origin-based classification into natural, semisynthetic, and synthetic, antibiotics may be divided into two broad groups according to their effect on microorganisms: those that kill bacteria are bactericidal agents, while those that only impair bacterial growth are known as bacteriostatic agents.
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