(Phys.org)—Beyond designing a drug that will attack cancer cells or bacterial cells, drug design also involves figuring out how the drug can safely enter the body and find its target before doing its work. However, many ...
(PhysOrg.com) -- New atomic-level "snapshots" published in the June 2, 2011, issue of Nature reveal details of how bacteria such as E. coli produce and secrete sticky appendages called pili, which help the microbes attach ...
Biochemistry
Jun 1, 2011
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Researchers report in the journal Nature that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that—once it infects a person—is notoriously ...
Cell & Microbiology
Nov 22, 2023
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15
Resistance to antibiotics is a problem that alarms the medical and scientific community. Bacteria resistant to three different classes of antibiotics, known as multi-drug resistant (MDR) bacteria, are far from rare. Some ...
Cell & Microbiology
May 15, 2023
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A team of researchers at the University of Queensland has discovered some of the mechanisms involved when bacteria become more resistant to antibacterial drugs after exposure to antidepressant drugs. In their paper published ...
Researchers have uncovered how some bacteria use electrical spikes to overcome antibacterial drugs, potentially leading to 'superbugs' that are resistant to antibiotics.
Cell & Microbiology
Jan 11, 2023
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National University of Singapore researchers have developed an approach to selectively target pathogenic bacteria by harnessing an intracellular metabolite known as formate, abundant in these bacteria, as a new antimicrobial ...
Biochemistry
Oct 9, 2020
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16
In a recent study in the Journal of The American Chemical Society, Professor Tewodros Asefa and Associate Professor Jeffrey Boyd synthesized nanostructured silica particles, considered to be promising drug carriers, that ...
Biochemistry
Oct 9, 2018
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75
A team of researchers working at Genentech with assistance from groups at RQx Pharmaceuticals and Wuxi AppTec has modified an arylomycin in a way that makes it effective against many drug-resistant bacteria. In their paper ...
Researchers at VIB, KU Leuven and UZ Leuven have devised a novel approach to develop antibacterial drugs. With antibiotic resistance on the rise worldwide, such new drugs are urgently needed. The Flemish biotech spin-off ...
Cell & Microbiology
Feb 28, 2018
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