An international team of researchers have discovered a new type of transition in protein folding: amyloid crystals formed from amyloid fibrils by a decrease in energy. The crystals are even more stable than the fibrils, which ...
Biochemistry
Nov 7, 2017
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12
A team of researchers from Germany and the Netherlands has determined the structure of an amyloid fibril with previously unachieved resolution. The fibrils of the body's own amyloid beta (Aβ) protein are the main constituent ...
Biochemistry
Sep 8, 2017
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744
Scientists at The Scripps Research Institute (TSRI) have developed a broadly useful method to unmask new functional features of human proteins.
Biochemistry
Nov 1, 2016
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185
Cambridge researchers have identified - and shown that it may be possible to control - the mechanism that leads to the rapid build-up of the disease-causing 'plaques' that are characteristic of Alzheimer's disease.
General Physics
Jul 18, 2016
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112
A metallic molecule being studied at Rice University begins to glow when bound to amyloid protein fibrils of the sort implicated in Alzheimer's disease. When triggered with ultraviolet light, the molecule glows much brighter, ...
Biochemistry
Jul 7, 2016
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12
Researchers from FOM Institute AMOLF have, for the first time ever, managed to make an image of the exterior structure of a protein aggregate that causes diseases like Alzheimer and type-2 diabetes. They discovered that the ...
Bio & Medicine
May 8, 2015
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615
Nature has many examples of self-assembly, and bioengineers are interested in copying or manipulating these systems to create useful new materials or devices. Amyloid proteins, for example, can self-assemble into the tangled ...
Bio & Medicine
Jan 26, 2015
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728
Yeast cells can sometimes reverse the protein misfolding and clumping associated with diseases such as Alzheimer's, according to new research from the University of Arizona.
Cell & Microbiology
Dec 9, 2014
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2
Scientists at The Scripps Research Institute (TSRI) have discovered a way to decrease deadly protein deposits in the heart, kidney and other organs associated with a group of human diseases called the systemic amyloid diseases.
Cell & Microbiology
Oct 23, 2014
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0
Swiss researchers have developed a new approach to measure proteins with structures that change. This could enable new diagnostic tools for the early recognition of neurodegenerative diseases to be developed.
Biotechnology
Sep 14, 2014
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