From good to bad with a copper switch

At the molecular level, the difference between Doctor Jekyll and Mr Hyde lies in a metal, copper. In its physiological form, the prion protein (PrPC ) is 'good' and is involved in normal body processes. It can happen, however, ...

Proteins with ALS, cancer role do not assume a regular shape

Gene expression, DNA repair, and protein making are intricate and vital processes, so it's a bit of a surprise in a new Brown University study that those processes depend significantly upon proteins that do not take a static ...

Physiologists uncover a new code at the heart of biology

UT Southwestern physiologists trying to understand the genetic code have found a previously unknown code that helps explain which protein should be created to form a particular type of cell.

Making nanowires from protein and DNA

The ability to custom design biological materials such as protein and DNA opens up technological possibilities that were unimaginable just a few decades ago. For example, synthetic structures made of DNA could one day be ...

Team shows a protein modification determines enzyme's fate

The human genome encodes roughly 20,000 genes, only a few thousand more than fruit flies. The complexity of the human body, therefore, comes from far more than just the sequence of nucleotides that comprise our DNA, it arises ...

Protein mimic shows promise as tissue engineering glue

Researchers have demonstrated the potential of a "synthetic protein mimic" to promote the adhesion of brain cells in a laboratory setting. This feat could help overcome a major challenge in nerve tissue engineering.

Life's underlying architecture shapes creation of proteins

Understanding how nature maps sequences of amino acids into the physical structure of the proteins they form is an old problem in biology, and a solution could open new doors to understanding the earliest forms of life—and ...

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