New cellular protective mechanism discovered

A vast number of biological reactions occur inside cells, generating various byproducts. Some of these can be highly reactive molecules, and if they build up inside cells they can cause stress and damage. One class of these ...

How a key immune protein is regulated in the cell

Scientists at EPFL have determined how a protein that is critical in our first line of immune defense is regulated in the cell to prevent autoinflammatory diseases.

Beyond AlphaFold: AI excels at creating new proteins

Over the past two years, machine learning has revolutionized protein structure prediction. Now, three papers in Science describe a similar revolution in protein design.

The origin of life in an RNA pocket

This story begins several billion years ago. There's only chemistry, no biology—that is, plenty of chemical compounds exist on Earth, but life hasn't yet emerged. Then, among myriads of randomly self-assembled chemical ...

New algorithm uncovers secrets of cell factories

Drug molecules and biofuels can be made to order by living cell factories, where biological enzymes do the job. Now, researchers at Chalmers University of Technology have developed a computer model that can predict how fast ...

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