Treating fungal cornea infection with synthetic molecules

A*STAR researchers have created synthetic molecules to treat fungal keratitis – an infection of the cornea that causes visual disability. The new molecules are a first step toward developing effective drugs to combat this ...

Spotting the invisible

Chemists at Umeå University have succeeded in mapping structures and functions of a transient enzyme state. By modifying the enzyme adenylate kinase, researchers were able to isolate the molecule and study it using the quantitative ...

Chemicals hitch a ride onto new protein for better compounds

Chemists have developed a powerful new method of selectively linking chemicals to proteins, a major advance in the manipulation of biomolecules that could transform the way drugs are developed, proteins are probed, and molecules ...

Proving the genetic code's flexibility

A, C, G and T - stand in for the four chemical bases that store information in DNA. A sequence of these same four letters, repeating in a particular order, genetically defines an organism. Within the genome sequence are shorter, ...

'Global positioning' for molecules

In everyday life, the global positioning system (GPS) can be employed to reliably determine the momentary location of one en route to the desired destination. Scientists from the Institute of Physical and Theoretical Chemistry ...

Introducing the multi-tasking nanoparticle

Kit Lam and colleagues from UC Davis and other institutions have created dynamic nanoparticles (NPs) that could provide an arsenal of applications to diagnose and treat cancer. Built on an easy-to-make polymer, these particles ...