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Merging cell datasets, panorama style

A new algorithm developed by MIT researchers takes cues from panoramic photography to merge massive, diverse cell datasets into a single source that can be used for medical and biological studies.

What artificial intelligence can teach us about proteins

Proteins are vital parts of all living organisms and perform essential tasks in our bodies. They build and repair tissues, supply components of the immune and hormone systems, regulate metabolism, and transmit signals. Researchers ...


In mathematics, computing, linguistics, and related subjects, an algorithm is a finite sequence of instructions, an explicit, step-by-step procedure for solving a problem, often used for calculation and data processing. It is formally a type of effective method in which a list of well-defined instructions for completing a task, will when given an initial state, proceed through a well-defined series of successive states, eventually terminating in an end-state. The transition from one state to the next is not necessarily deterministic; some algorithms, known as probabilistic algorithms, incorporate randomness.

A partial formalization of the concept began with attempts to solve the Entscheidungsproblem (the "decision problem") posed by David Hilbert in 1928. Subsequent formalizations were framed as attempts to define "effective calculability" (Kleene 1943:274) or "effective method" (Rosser 1939:225); those formalizations included the Gödel-Herbrand-Kleene recursive functions of 1930, 1934 and 1935, Alonzo Church's lambda calculus of 1936, Emil Post's "Formulation 1" of 1936, and Alan Turing's Turing machines of 1936–7 and 1939.

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