Amyloids are protein aggregates that can form in the body, sometimes leading to diseases such as Alzheimer's. These fibrils can adopt multiple shapes, known as "polymorphs," which complicate our understanding of their role ...
Molecular & Computational biology
Jul 16, 2024
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0
Could measuring protein clumps in our cells be a new way to find out our risk of getting age-related diseases? Professor Dorothee Dormann and Professor Edward Lemke of Johannes Gutenberg University Mainz (JGU), who are also ...
Cell & Microbiology
Jun 17, 2024
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16
Proteins are vital biomolecules responsible for performing various functions in the human body and are thus regarded as the workhorses of a cell. The primary structure of a protein is composed of different amino acids coming ...
Biochemistry
May 30, 2024
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55
Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells (HSCs) are remarkably long-lived. HSCs are blood-forming cells—they give rise to rapidly dividing progenitor cells, which in turn ...
Cell & Microbiology
Apr 30, 2024
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60
Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without incurring damage. In mice, ...
Cell & Microbiology
Feb 20, 2024
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70
Researchers led by Prof. Wang Lei from the Institute of Biophysics of the Chinese Academy of Science (CAS) and their collaborators have identified the direct target of vinigrol as protein disulfide isomerase (PDI) on the ...
Biochemistry
Nov 16, 2023
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25
Researchers at the IBB-UAB have developed the most comprehensive database available to date to help understand the basis of protein aggregation, a phenomenon associated with aging and several pathologies. The new resource, ...
Molecular & Computational biology
Nov 3, 2023
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1
Researchers from the Babraham Institute, UK, and the German Center for Neurodegenerative Diseases (DZNE) have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation ...
Molecular & Computational biology
Sep 14, 2023
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40
A couple of months each year, groupers (Epinephelidae) gather in the hundreds and even thousands to mate under the full moon. This concentrated nature and short duration of mating, however, renders these species susceptible ...
Plants & Animals
Aug 9, 2023
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18
Microparticle dust aggregates, which are thought to play a role in the formation of new planets, are less likely to stick together after a collision when the aggregates are larger.
Planetary Sciences
Jul 21, 2023
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