Exploring the limits of a new kind of chemo

Chemotherapy sucks. The treatments generally have awful side effects, and it's no secret that the drugs involved are often toxic to the patient as well as their cancer. The idea is that, since cancers grow so quickly, chemotherapy ...

First structure of key COVID enzyme at human body temperature

Scientists studying a COVID-19 coronavirus enzyme at temperatures ranging from frosty to human-body warm discovered subtle structural shifts that offer clues about how the enzyme works. The findings, published in IUCrJ, the ...

Mapping electric fields to help unravel how enzymes work

Every moment in our bodies' cells, countless activities vital to life occur thanks to enzymes. These special proteins act as catalysts by accelerating the pace and improving the selectivity of chemical reactions without undergoing ...

Enzyme in human salivary microbes decomposes PET-based plastics

Human saliva may contain an enzyme which can decompose the plastic polyethylene terephthalate (PET). Researchers found the promising enzyme, a hydrolase, in a database containing human metagenome samples. As they report in ...

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