How rhomboid protease activity is regulated

Rhomboid proteases are a promising target for new drugs. Now researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have uncovered a mechanism for regulating enzyme activity. The key role is played ...

How cells rapidly create protrusions for exploration and movement

In order to move, cells must be able to rapidly change shape. A team of researchers from the University of North Carolina at Chapel Hill show that cells achieve this by storing extra "skin" in folds and bumps on their surface. ...

A new, sustainable source for a promising cancer killer

Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value. One of these hidden gems is (–)-jerantinine A (JA), a molecule with remarkable anticancer properties, ...

Team co-maps proteins and transcriptome in human tissues

To understand how cells behave, researchers also need to understand the molecules that make them work. "If someone wants to know how the kidney functions, they have to know what's going on inside the kidney cells," says Yang ...

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