Search results for organ-on-a-chip

Materials Science Mar 7, 2018

More realistic and accurate organs-on-chips

In a step toward better diagnosis and treatment of digestive conditions, such as inflammatory bowel disease, scientists report in ACS Biomaterials & Engineering that they have developed a first-of-its-kind collagen-based ...

Bio & Medicine Mar 31, 2023

New study offers clues into how cancer spreads to the brain

When cancer spreads to the brain, treatment options fall off. Most of the drugs designed to target metastases do not cross the blood-brain barrier or are ineffective at treating brain metastases.

Biochemistry Jul 22, 2016

Researchers develop placenta-on-a-chip

Researchers at the University of Pennsylvania have developed the first placenta-on-a-chip that can fully model the transport of nutrients across the placental barrier.

Cell & Microbiology Oct 12, 2022

Developing an organic transmembrane device to host and monitor 3-D cell cultures

Researchers have used 3D cell culture models in the past decade to translate molecular targets during drug discovery processes to thereby transition from an existing predominantly 2D culture environment. In a new report now ...

Optics & Photonics Aug 20, 2021

New imaging tool visualizes cell functions in a microphysiological system

A microphysiological system (MPS), also known as an organ-on-a-chip, is a 3D organ construct using human cells that help reveal how organs respond to drugs and environmental stimuli.

Analytical Chemistry Jan 15, 2014

Portable instrument that replaces full-size laboratory provides accurate multi-element analysis in less than a minute

Engineers from the A*STAR Institute of Materials Research and Engineering and colleagues at the University of Basel, Switzerland, have designed and developed a compact, portable analytical instrument that can detect multiple ...

Analytical Chemistry Oct 25, 2018

New chip measures multiple cellular responses to speed drug discovery

Finding ways to improve the drug development process – which is currently costly, time-consuming and has an astronomically high failure rate – could have far-reaching benefits for health care and the economy. Researchers ...

Cell & Microbiology Mar 28, 2023

Skin-on-a-chip: Modeling an innervated epidermal-like layer on a microfluidic chip

Bioengineers and tissue engineers intend to reconstruct skin equivalents with physiologically relevant cellular and matrix architectures for basic research and industrial applications. Skin pathophysiology depends on skin-nerve ...

Cell & Microbiology Jan 27, 2023

Fish-on-Chips: An optofluidic platform to investigate the neural and chemosensory axes of zebrafish

Neuroscientists study chemosensory processing by establishing chemical cues and the corresponding behavioral responses to record large-scale neuronal activity. In a new report now published in Nature Communications, Samuel ...

Biotechnology Mar 9, 2015

Bioengineers put human hearts on a chip to aid drug screening

When University of California, Berkeley, bioengineers say they are holding their hearts in the palms of their hands, they are not talking about emotional vulnerability.

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