Search results for Eukaryote

Cell & Microbiology Feb 10, 2023

Autophagy: The molecular regulation of self-eating

Autophagy, or "self-eating", is an essential cellular quality control mechanism that clears the cell of protein aggregates and damaged organelles. This mechanism is inactive under normal conditions and only triggered upon ...

Cell & Microbiology Feb 10, 2023

Researchers use cryo-electron microscopy to reveal structural changes that temporarily shut down RNA synthesis

Precise control of gene expression—ensuring that cells make the correct components in the right amount and at the right time—is vital for all organisms to function properly. Cells must regulate how genes encoded in the sequence ...

Cell & Microbiology Jan 18, 2023

New study decodes one of the world's fastest cell movements

Heliozoan axopodia are important for their motility. However, the underlying mechanism of their axopodial contraction has remained ambiguous. Recently, researchers from the Okayama University reported that microtubules are ...

General Physics Jan 6, 2023

Physicists find that organelles grow in random bursts

Eukaryotic cells—the ones that make up most life as we know it, including all animals, plants and fungi—are highly structured objects.

Molecular & Computational biology Jan 5, 2023

Lost in translation: How 'risky' amino acids abort elongation in protein synthesis

Life depends on the precise functioning of several proteins synthesized in cells by ribosomes. This diverse set of proteins, known as a proteome, is maintained by the robust translation elongation of amino acid sequences ...

Molecular & Computational biology Jan 4, 2023

New insights into a fundamental process in mitochondria

Researchers at Karolinska Institutet have uncovered the function of the release factor mtRF1 in the final steps of mitochondrial protein synthesis. The study, published in Nature Communications, reveals new insights into ...

Evolution Dec 21, 2022

Shedding light on the origin of complex life forms

How did the complex organisms on Earth arise? This is one of the big open questions in biology. A collaboration between the working groups of Christa Schleper at the University of Vienna and Martin Pilhofer at ETH Zurich ...

Molecular & Computational biology Dec 20, 2022

Ribosomes search AUG codons in bidirectional scanning, challenging the first-AUG rule

Translation, a process that expresses the genetic information from messenger RNA (mRNA) to protein, is vital to maintain cellular protein homeostasis. To synthesize functional proteins and avoid toxic translation products, ...

Evolution Dec 20, 2022

When was the first time life began to prey on each other?

Using the word predation may seem surprising when we talk about the first organisms that set out to eat other organisms, for they were not deadly predators with sharp teeth and claws, but small single-celled life forms that ...

Biochemistry Dec 9, 2022

Discovery of critical inhibitory site in an energy-producing enzyme could lead to the rational design of antibiotics

Antimicrobial resistance (AMR) is a global health problem. Species of drug-resistant pathogens, including Neisseria gonorrhoeae, could become untreatable due to a high degree of AMR.

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