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General Physics Feb 17, 2022

Vortex microscope sees more than ever before

Understanding the nitty gritty of how molecules interact with each other in the real, messy, dynamic environment of a living body is a challenge that must be overcome in order to understand a host of diseases, such as Alzheimer's.

Cell & Microbiology Feb 10, 2022

Mitochondria efficiently adapt to changing metabolic conditions

A recent study explains an essential component for proper mitochondrial function: The protein complexes MICOS and ATP synthase can communicate with each other. Dr. Heike Rampelt and Prof. Dr. Nikolaus Pfanner at the Institute ...

Cell & Microbiology Jan 13, 2022

Deadly combination: New direct trigger for cell death discovered

Scientists led by Professor Ana J. Garcia-Saez at the CECAD Cluster of Excellence for Aging Research at the University of Cologne have shown that apoptosis, the programmed cell death, involves a direct physical interplay ...

Bio & Medicine Jan 7, 2022

Visualizing intracellular nanostructures of living cells using nanoendoscopy-AFM

Atomic force microscopy (AFM) offers a method for label-free imaging of nanoscale biomolecular dynamics to solve biological questions that cannot be addressed via other bioimaging methods including fluorescence and scanning ...

Bio & Medicine Jan 6, 2022

Decoding protein assembly dynamics with artificial protein needles

Protein assembly is essential for the formation of ordered biological structures, but imagine engineering one. This is exactly what researchers at Tokyo Tech have now accomplished with protein needles. By regulating the tip-to-tip ...

Optics & Photonics Jan 4, 2022

Ultrafast imaging of terahertz electric waveforms using quantum dots

Microscopic electric fields govern a remarkable variety of phenomena in condensed matter and their ultrafast evolutions drive plasmonics, phononics and highspeed nanoelectronics. Access to high-frequency electric waveforms ...

Biotechnology Dec 27, 2021

Fluorescence lifetime imaging for studying DNA compaction and gene activities

Studies of the genomic DNA compaction in the cell nucleus and dynamic reorganization during physiologic processes or disease development in live cell environments are exceedingly challenging. This complexity stems from a ...

Analytical Chemistry Dec 20, 2021

Sneezes, rain clouds and ink jets: Improving the ability of optical microscopes to measure the volume of microdroplets

Sneezes, rain clouds, and ink jet printers: They all produce or contain liquid droplets so tiny it would take several billion of them to fill a liter bottle.

Optics & Photonics Dec 13, 2021

Using cold to enhance microscopy

Fluorescence light microscopy has the unique ability to observe cellular processes over a scale that bridges four orders of magnitude. Yet, its application to living cells is fundamentally limited by the very rapid and unceasing ...

Materials Science Dec 10, 2021

A needle in a haystack: Weeding out dead catalyst

Catalysts are important additives that are used to increase the material and energy efficiency of chemical reactions and processes. Although catalysts operate in cycles that should restore their initial activity over and ...

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