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Bio & Medicine Aug 6, 2024

The shape of molecules to come: A Q&A on designing DNA nanostructures for biomedical applications

By discovering new ways to manipulate matter at the atomic and molecular levels, advances in nanotechnology are paving the way for innovations in medicine, electronics, materials science and environmental remediation, among ...

Molecular & Computational biology Jun 26, 2024

Scientists discover next-generation system for programmable genome design

In a leap forward for genetic engineering, a team of researchers from the Arc Institute has discovered the bridge recombinase mechanism, a precise and powerful tool to recombine and rearrange DNA in a programmable way.

Biotechnology Jun 21, 2024

Beyond CRISPR: seekRNA delivers a new pathway for accurate gene editing

Scientists at the University of Sydney have developed a gene-editing tool with greater accuracy and flexibility than the industry standard, CRISPR, which has revolutionized genetic engineering in medicine, agriculture and ...

Biotechnology Jun 4, 2024

Scientists push single-molecule DNA sequencing to the next level

In recent years, technologies that allow scientists to study a person's DNA at single-molecule resolution have vastly expanded our knowledge of the human genome, the microbiome, and the genetic basis of disease. With such ...

Plants & Animals May 29, 2024

Complete X and Y chromosome sequences of living great ape species determined

Newly generated, complete "end-to-end" reference genomes for the sex chromosomes of five great ape species and one lesser ape species—produced by an international collaborative team led by researchers at Penn State, the National ...

Bio & Medicine May 9, 2024

New DNA origami technique promises advances in medicine

A new technique in building DNA structures at a microscopic level has the potential to advance drug delivery and disease diagnosis, a study suggests.

Molecular & Computational biology Apr 12, 2024

Developing a machine learning model to explore DNA methylation

A Northwestern Medicine study has detailed the development of a machine learning model to predict DNA methylation status in cell-free DNA by its fragmentation patterns, according to findings published in Nature Communications.

Cell & Microbiology Apr 11, 2024

Biologists reveal how gyrase resolves DNA entanglements

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in every cell in the body ...

Evolution Apr 1, 2024

Ancient Adélie penguin DNA reveals that small repeats persist for hundreds of millions of years

Microsatellites are valuable tools for studying inheritance, genetic diversity, and population dynamics across a wide range of organisms including bacteria, plants, animals, and fungi. These short, repeating sequence motifs ...

Plants & Animals Mar 6, 2024

Early life adversity leaves long-term signatures in baboon DNA

Early experiences in an animal's life can have a significant impact on its capacity to thrive, even years or decades later, and DNA methylation may help record their effects.

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