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Biochemistry Jun 21, 2021

Universal mechanism of regulation in plant cells discovered

All plant cells obtain their energy mainly from two organelles they contain—chloroplasts (responsible for photosynthesis) and mitochondria (responsible for the biochemical cycle of respiration that converts sugars into energy). ...

Cell & Microbiology Jun 4, 2021

The cut and restore protein trick: Self-excising designer proteins

Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. A new bioengineered reporter system developed at ...

Biotechnology May 21, 2021

Using CRISPR to lower cholesterol levels in monkeys

A team of researchers from Verve Therapeutics and the Perelman School of Medicine at the University of Pennsylvania has developed a CRISPR gene-editing technique that lowered the levels of cholesterol in the blood of test ...

Cell & Microbiology May 12, 2021

Researchers reveal the internal signals cells use to maintain energy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have taken a deep dive into a previously overlooked family of proteins and discovered that they are essential to maintaining the energy that cells need to grow ...

Biotechnology Apr 29, 2021

Researchers discover a new diet-dependent mechanism for regulating RNA maturation

Particularly sensitive to chemical modifications, messenger RNAs (mRNAs) are molecules responsible for transmitting the information encoded in our genome, allowing for the synthesis of proteins, which are necessary for the ...

Molecular & Computational biology Apr 14, 2021

RNA holds the reins in bacteria: Researchers observe RNA controlling protein synthesis

To better understand how RNA in bacteria gives rise to protein—and along the way, target these processes in the design of new antibiotics—researchers are turning their attention to the unique way this process happens in bacteria.

Environment Apr 12, 2021

Bottom-up is the way forward for nitrogen reduction at institutions

Nitrogen is an element basic for life—plants need it, animals need it, it's in our DNA—but when there's too much nitrogen in the environment, things can go haywire. On Cape Cod, excess nitrogen in estuaries and salt marshes ...

Biotechnology Apr 12, 2021

What is mRNA? What you should know about the key ingredient in some COVID-19 vaccines

One surprising star of the coronavirus pandemic response has been the molecule called mRNA. It's the key ingredient in the Pfizer and Moderna COVID-19 vaccines. But mRNA itself is not a new invention from the lab. It evolved ...

Cell & Microbiology Mar 17, 2021

Researchers identify non-coding RNA molecule in trypanosome parasites

Trypanosomatids are single-cell parasites that cause major diseases, such as sleeping sickness and Rose of Jericho, which affect millions of people. Trypanosoma parasites are transmitted to mammals by the blood-sucking tsetse ...

General Physics Mar 11, 2021

Tracking cosmic ghosts

The idea was so far-fetched it seemed like science fiction: create an observatory out of a one cubic kilometer block of ice in Antarctica to track ghostly particles called neutrinos that pass through the Earth. But speaking ...

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