Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or viral intruders. The PRRs forward the signals which results in the production of interferons, which ...
Mitochondria are essential for cell survival, repair, and adaptation. Not only do they generate most of the energy needed during a cell's life, but they also regulate cell death, calcium balance, and responses to stress. ...
After more than a decade of research, scientists have discovered the natural mechanism behind a novel form of cell death called ferroptosis. The work, described in the current issue of Cell, points toward an entirely new ...
The laser you see in the photo above may one day enhance images taken by the most powerful microscopes in biology. This advancement, detailed in a paper published in eLife from scientists at Columbia's Zuckerman Institute ...
A novel method to manipulate the inner structure of cells connects several scientific fields and could represent a significant step in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. ...
NBA teams that paid their core players inequitably won fewer games as a result of reduced cooperation, according to a Washington State University study with implications for workplace management. While it draws on data from ...
A multi-institutional team of researchers led by Virginia Tech's Fralin Biomedical Research Institute at VTC has for the first time identified specific patterns of brain chemical activity that predict how quickly individual ...
Cornell researchers have discovered a new way cells regulate how they respond to stress, identifying an interaction between two proteins that helps keep a critical cellular recycling system in balance. The findings show that ...
A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the intrinsically disordered translational ...
A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top 200 small-molecule drugs ...
