A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the intrinsically disordered translational ...
A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top 200 small-molecule drugs ...
An international team of researchers including scientists from The Australian National University (ANU) have developed a way to reveal the smallest of malfunctions in the biochemical machinery that makes proteins in our bodies. ...
Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is known to regulate cytosolic-side functions such as membrane fusion/fission, movement, and membrane-contact ...
Beachgoers in Australia are on high alert following four shark incidents in New South Wales in 48 hours.
For more than 25 years, humans have lived and worked continuously aboard the International Space Station, conducting research that is transforming life on Earth and shaping the future of exploration. From growing food and ...
Neuromorphic computers, inspired by the architecture of the human brain, are proving surprisingly adept at solving complex mathematical problems that underpin scientific and engineering challenges.
A new study from Bar-Ilan University shows that one of sleep's core functions originated hundreds of millions of years ago in jellyfish and sea anemones, among the earliest creatures with nervous systems. By tracing this ...
In a recent study published in the Cambridge Archaeological Journal, Dr. Bernardo Arriaza argues that the practice of artificial mummification among the Chinchorro people may have evolved as a response to high infant mortality ...
Researchers in the Department of Theoretical Physics at Tata Institute of Fundamental Research (TIFR), Mumbai, have discovered that instead of manipulating every component or modifying interactions in a many-body system, ...
