Search results for parkinson

Molecular & Computational biology Jan 16, 2024

Unraveling the role of supersulfides in regulating mitochondrial function and longevity

Supersulfides are gaining prominence for their occurrence as low-molecular-weight thiols or persulfidated cysteine residues, observed more frequently in both prokaryotic and eukaryotic cells. These compounds, which are characterized ...

Ecology Jan 15, 2024

Fossil holdfasts show kelp far predate animals we see in kelp forests today

The unique underwater kelp forests that line the Pacific Coast support a varied ecosystem that was thought to have evolved along with the kelp over the past 14 million years.

Evolution Jan 13, 2024

Discoveries gleaned from ancient human DNA

Four research articles published in Nature follow the genetic traces and geographical origins of human diseases far back in time. The analyses provide detailed pictures of prehistoric human diversity and migration, while ...

Cell & Microbiology Jan 12, 2024

Cellular clean energy: Can mitochondria make more energy without collateral damage?

Is it possible to amp up the energy production of mitochondria without also boosting potentially harmful byproducts? If so, such a method could be used to treat a host of neurodegenerative diseases in which impaired mitochondria ...

Cell & Microbiology Dec 14, 2023

Discovery reveals lipid-signaling microdomains in cells

Important signaling molecules called phospholipids are active throughout cells in small compartments called condensates, rather than functioning primarily in cell membranes as previously thought, according to a study from ...

Cell & Microbiology Dec 12, 2023

Scientists discover how bacteria build protein signals in cells during infection

New research from Oregon Health & Science University could one day lead to therapies that prevent or treat diseases and infections tied to a protein that's found in all human cells.

Molecular & Computational biology Dec 8, 2023

Structure of a central component of the human immune system revealed

A central component of the human immune system, the NLRP3 inflammasome plays an important role in fighting off infections. However, its chronic activation is also implicated in a variety of common diseases, such as Alzheimer's, ...

Bio & Medicine Dec 5, 2023

Using solid-state nanopores and DNA barcoding to identify misfolded proteins in neurodegenerative disorders

A team of chemists, microbiologists and physicists at the University of Cambridge in the U.K. has developed a way to use solid-state nanopores and multiplexed DNA barcoding to identify misfolded proteins such as those involved ...

Cell & Microbiology Nov 24, 2023

Scientists reveal how RNA gets spliced correctly

To carry out all of life's functions, proteins must be produced from instructions carried by genes within DNA and delivered to the cell's protein-making machinery by messenger RNA.

Bio & Medicine Nov 21, 2023

Nano-sized probes reveal how cellular structure responds to pressure

By giving living cells a "nano-poke" and monitoring the resulting changes in the intracellular environment, researchers have gotten their first glimpse of how whole cells respond to external mechanical pressure.

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