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Other Oct 4, 2017

Three researchers win Nobel Prize in Chemistry for developments in electron microscopy

A revolutionary technique dubbed cryo-electron microscopy, which has peered closer at the Zika virus and an Alzheimer's enzyme, earned scientists Jacques Dubochet, Joachim Frank and Richard Henderson the Nobel Chemistry ...

Optics & Photonics Jun 15, 2021

Novel calibration procedure for super-resolution brain imaging

Light—and all waves—can bend around the corners of obstacles found along its path. Because of this phenomenon, called diffraction, it is impossible to focus light onto a spot that is smaller than half its wavelength. ...

Cell & Microbiology Jan 22, 2015

New mechanism unlocked for evolution of green fluorescent protein

A primary challenge in the biosciences is to understand the way major evolutionary changes in nature are accomplished. Sometimes the route turns out to be very simple. An example of such simplicity is provided in a new publication ...

Analytical Chemistry Nov 27, 2023

New fluorescence-based methods for fast and accessible light intensity measurements

Accurate measurements of light intensity provide vital data for scientists and everyday applications. For example, precise values help optimize microscopy signals, trigger physiological processes in the brain, and drive light-absorbing ...

Cell & Microbiology Oct 3, 2023

Fluorescent and radiometric probes provide researchers with more detailed data

The University of Cincinnati's Jiajie Diao and Yujie Sun have a simple approach to research: Keep an open mind, and follow the data wherever it leads.

Biotechnology Apr 18, 2023

Team develops new barcoded gene reporter system for electron microscopy

How do the nerve cells in our brain communicate with each other? What processes take place when T cells render cancer cells harmless? Details of the mechanisms at the cellular level remain hidden from view. Now, special reporter ...

Optics & Photonics Aug 27, 2019

Computational approach speeds up advanced microscopy imaging

Researchers have developed a way to enhance the imaging speed of two-photon microscopy up to five times without compromising resolution. This record-fast imaging speed will allow scientists to observe biological phenomena ...

Analytical Chemistry May 7, 2018

Better together: Merged microscope offers unprecedented look at biological processes

Scientists at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have combined two different microscope technologies to create sharper images of rapidly moving processes inside a cell.

Biotechnology Apr 22, 2024

New super-resolution microscopy approach visualizes internal cell structures and clusters via selective plane activation

To study living organisms at ever smaller length scales, scientists must devise new techniques to overcome the so-called diffraction limit. This is the intrinsic limitation on a microscope's ability to focus on objects smaller ...

Optics & Photonics Sep 21, 2022

New endoscope uses bendable GRIN lens for 3D microscopy

Researchers have created a flexible needle-like endoscopic imaging probe that can acquire 3D microscopic images of tissue. The bendability is possible thanks to a new flexible graded index (GRIN) lens developed by the researchers.

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