Search results for organ-on-a-chip applications

Analytical Chemistry Mar 12, 2025

How do researchers determine how toxic a chemical is? A toxicologist explains alternatives to animal testing

A vast number of chemicals are registered for production and use around the world. But only a portion have been thoroughly evaluated for their toxicity due to time, cost, ethical concerns and regulatory limitations.

Optics & Photonics Feb 25, 2025

A completely new type of microscopy based on quantum sensors

Researchers at the Technical University of Munich (TUM) have invented an entirely new field of microscopy called nuclear spin microscopy. The team can visualize magnetic signals of nuclear magnetic resonance with a microscope. ...

Bio & Medicine Jan 29, 2025

Droplet microfluidics advance may hold key to next-generation cancer drugs

At Texas A&M University, one research lab is changing the game of droplet microfluidics, a technique that involves conducting experiments in nanoscale droplets of liquid in a controlled environment. The team has developed ...

Biochemistry Jan 14, 2025

Scientists develop self-assembling molecules with potential applications in targeted drug delivery

Scientists have taken a major step forward in tackling one of the greatest abiding challenges in chemistry, by learning how to program the self-assembly of molecules in such a way that the end result is predictable and desirable.

Cell & Microbiology Aug 29, 2019

Pancreas on a chip: Scientists combine organ-on-a-chip and stem-cell technologies

By combining two powerful technologies, scientists are taking diabetes research to a whole new level. In a study led by Harvard University's Kevin Kit Parker, microfluidics and human, insulin-producing beta cells have been ...

Biotechnology Aug 28, 2019

Organ-on-a-chip: 3-D self-rolled biosensor array to electrically interrogate electrogenic cells

Cell to cell communication plays an important role in coordinating the function of biological systems. Three-dimensional (3-D) spheroids (cell aggregates) allow biologists to explore cellular communication during tissue development ...

Analytical Chemistry Oct 5, 2017

Scientists develop 'body-on- a-chip' system to accelerate testing of new drugs

Using the same expertise they've employed to build new organs for patients, scientists at Wake Forest Institute for Regenerative Medicine and colleagues have engineered micro hearts, lungs and livers that can potentially ...

Analytical Chemistry Jan 17, 2019

3-D culturing hepatocytes on a liver-on-a-chip device

Liver-on-a-chip cell culture devices are attractive biomimetic models in drug discovery, toxicology and tissue engineering research. To maintain specific liver cell functions on a chip in the lab, adequate cell types and ...

Nanophysics Jun 21, 2021

A cavitation-on-a-chip device with a multiple microchannel configuration

Hydrodynamic cavitation is a major phase change phenomena that can occur with a sudden decrease in the local static pressure within a fluid. The emergence of microelectromechanical systems (MEMS) and high-speed microfluidic ...

Biotechnology Jan 16, 2018

'Heart-on-a-chip' process aims to speed up drug testing

Testing new clinical drugs' effect on heart tissue could become quicker and more straightforward, thanks to new research from Harvard University.

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