Search results for organ-on-a-chip applications

Analytical Chemistry Oct 5, 2017

Scientists develop 'body-on- a-chip' system to accelerate testing of new drugs

Using the same expertise they've employed to build new organs for patients, scientists at Wake Forest Institute for Regenerative Medicine and colleagues have engineered micro hearts, lungs and livers that can potentially ...

Analytical Chemistry Jan 17, 2019

3-D culturing hepatocytes on a liver-on-a-chip device

Liver-on-a-chip cell culture devices are attractive biomimetic models in drug discovery, toxicology and tissue engineering research. To maintain specific liver cell functions on a chip in the lab, adequate cell types and ...

Nanophysics Jun 21, 2021

A cavitation-on-a-chip device with a multiple microchannel configuration

Hydrodynamic cavitation is a major phase change phenomena that can occur with a sudden decrease in the local static pressure within a fluid. The emergence of microelectromechanical systems (MEMS) and high-speed microfluidic ...

Biotechnology Jan 16, 2018

'Heart-on-a-chip' process aims to speed up drug testing

Testing new clinical drugs' effect on heart tissue could become quicker and more straightforward, thanks to new research from Harvard University.

Analytical Chemistry Feb 8, 2017

Scientists create organs-on-chips for large-scale drug screening

Led by UCI professor of molecular biology & biochemistry Christopher C.W. Hughes, the research team successfully established multiple vascularized micro-organs on an industry-standard 96-well plate. Hughes and the study's ...

Cell & Microbiology Feb 7, 2023

Biosensor could lead to new drugs, sensory organs on a chip

A synthetic biosensor that mimics properties found in cell membranes and provides an electronic readout of activity could lead to a better understanding of cell biology, development of new drugs, and the creation of sensory ...

Biotechnology Jun 17, 2019

Inducing an osteoarthritic (OA) phenotype in a cartilage-on-a-chip (COC) model

In an aging population, the social impact of osteoarthritis (OA) can dramatically increase to become the most common musculoskeletal disease. However, at present, therapies are limited to palliative treatments or surgical ...

General Physics Apr 22, 2011

Optical microscope without lenses produces high-resolution 3-D images on a chip

(PhysOrg.com) -- UCLA researchers have redefined the concept of a microscope by removing the lens to create a system that is small enough to fit in the palm of a hand but powerful enough to create three-dimensional tomographic ...

Analytical Chemistry Apr 4, 2012

IBN's 'fish and chips' may help accelerate drug discovery

A cheaper, faster and more efficient platform for preclinical drug discovery applications has been invented by scientists at the Institute of Bioengineering and Nanotechnology (IBN), the world’s first bioengineering ...

Cell & Microbiology Oct 12, 2022

Developing an organic transmembrane device to host and monitor 3-D cell cultures

Researchers have used 3D cell culture models in the past decade to translate molecular targets during drug discovery processes to thereby transition from an existing predominantly 2D culture environment. In a new report now ...

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