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Evolution 1 hour ago

Crabs have evolved five separate times—why do the same forms keep appearing in nature?

Charles Darwin believed evolution created "endless forms most beautiful." It's a nice sentiment but it doesn't explain why evolution keeps making crabs.

Optics & Photonics 3 hours ago

Telescope-inspired microscope sees molecules in 6D

A new technology, inspired in part by the design of the James Webb Space Telescope (JWST), uses mirror segments to sort and collect light on the microscopic scale, and capture images of molecules with a new level of resolution: ...

Cell & Microbiology 5 hours ago

Developmental genetics: How germ cells cut the cord from their parents

For the first cell to develop into an entire organism, genes, RNA molecules and proteins have to work together in a complex way. At first, this process is indirectly controlled by the mother. At a certain point in time, the ...

Biochemistry 6 hours ago

Directly visualizing the cooperative adsorption of a string-like molecule onto a solid with double-stranded DNA

Macromolecules in diverse phases can adsorb onto natural systems, composite materials, and thin-film devices. In a new report now published in Science Advances, Yuma Morimitsu and a research team in applied chemistry and ...

Cell & Microbiology 6 hours ago

Key proteins keep DNA regions close for longer

New work by Friedrich Miescher Institute researchers shows that key proteins help to stabilize the interaction between otherwise highly dynamic DNA structures. The findings shed light onto how the complex folds that help ...

Cell & Microbiology 6 hours ago

How chemical modifications on DNA keep genes silent

Several diseases, including certain types of cancer and some neurodevelopmental conditions, have aberrant patterns of DNA methylation, a chemical modification that regulates gene expression in ways that keep genes in the ...

Optics & Photonics 7 hours ago

Researchers adapt a Nobel Prize-winning method to design new, ultra-powerful X-ray systems

If scientists want to push the boundaries of, say, an X-ray laser, they may need to create some new technology. But occasionally there's no need to reinvent the wheel. Instead, scientists simply come up with a new way to ...

Evolution 23 hours ago

More flexible than we thought: Worms provide new insights into the evolution and diversification of TGF-beta signaling

The TGF-ß cellular signaling network, essential to various functions in all metazoans and involved in many severe human pathologies like autoimmune diseases and cancer, is more flexible than previously thought.

Biochemistry Dec 05, 2022

Team reveals extraordinary plasticity of the glucocorticoid receptor

Glucocorticoids—such as cortisone—are among the most widely used anti-inflammatory drugs, and are used to treat asthma, psoriasis, organ transplantation and even COVID-19. Regarding their pharmacological action, the activity ...

Optics & Photonics Dec 05, 2022

Measuring times in billionths of a billionth of a second

How fast do electrons inside a molecule move? Well, it is so fast that it takes them just a few attoseconds (a billionth of billionth of a second) to jump from one atom to another. Blink and you missed it—millions of billions ...

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