Engineering a new color palette for single-molecule imaging
Researchers often study biomolecules such as proteins or amino acids by chemically attaching a "fluorophore," a sensitive molecule that absorbs and re-emits energy from light.
Researchers often study biomolecules such as proteins or amino acids by chemically attaching a "fluorophore," a sensitive molecule that absorbs and re-emits energy from light.
Scientists have developed a water-soluble, non-toxic fluorescent spray that makes fingerprints visible in just a few seconds, making forensic investigations safer, easier and quicker.
SMU nanotechnology expert MinJun Kim helped a team of researchers at The University of Texas at Austin to develop a less expensive way to detect nuclease digestion—one of the critical steps in many nucleic acid sensing ...
When Senior Scientist Jonathan Grimm came to Janelia 13 years ago, he didn't know much about fluorescence or fluorescent dyes. But as an organic chemist who had been working in drug discovery at Merck, he certainly knew a ...
PFAS, a family of highly fluorinated substances, represent a danger for humans and the environment. Particularly problematic members of this family, such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) ...
The 2023 Nobel Prize for chemistry isn't the first Nobel awarded for research in nanotechnology. But it is perhaps the most colorful application of the technology to be associated with the accolade.
Cancer surgeons may soon have a more complete view of tumors during surgery, thanks to new imaging agents that can illuminate multiple biomarkers at once, University of Illinois Urbana-Champaign researchers report. The fluorescent ...
Quick assessment of trace blood components in untreated blood samples is possible with fluorescence tests but, in practice, blood's strong autofluorescence interferes with the analysis. In the journal Angewandte Chemie International ...
Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism ...
Inspired by the mechanism behind light-sensitive sunglasses, a team led by a North Carolina State University researcher invented a family of fluorescent dyes to illuminate biological processes at a very small scale—comparable ...