Commonly used chemical fixation causes aggregation artifact
Researchers at Kanazawa University report in Communications Biology that using common chemicals for fixing living cell samples for microscopy studies causes membrane proteins to aggregate.
Researchers at Kanazawa University report in Communications Biology that using common chemicals for fixing living cell samples for microscopy studies causes membrane proteins to aggregate.
Biochemistry
Aug 10, 2022
0
24
Researchers at Kanazawa University report in the Journal of Physical Chemistry Letters how to simulate 3D atomic force microscopy images of out-of-equilibrium systems involving biomolecules. The approach makes use of a celebrated ...
Biochemistry
Jul 25, 2022
0
8
Atomic force microscopy (AFM) allows us to visualize the dynamics of single biomolecules during their functional activity. All observations are, however, restricted to regions accessible by a fairly big probing tip during ...
Biotechnology
Jul 6, 2022
0
142
Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed ...
Cell & Microbiology
Jun 29, 2022
0
5
Researchers at Kanazawa University in collaboration with teams from Toyama Prefectural University and BioSeeds Corporation report in ACS Applied Materials & Interfaces the identification of a molecule with enhanced antiproliferative ...
Biochemistry
Jun 8, 2022
0
97
Tetraphenylammonium, with all four hydrogens of ammonium (NH4+) replaced with benzene rings, has neither been discovered in nature nor chemically synthesized, calling into question whether it could exist. Here, we succeeded ...
Analytical Chemistry
Jun 3, 2022
0
122
Tile patterns in which the same shape is laid out without gaps can be seen on castle walls and chess boards in artificial objects, and in insect compound eyes and beehives in biology. Square tiles are common in artificial ...
Plants & Animals
May 13, 2022
0
3
Amyloidosis is the collective name for a group of diseases characterized by the deposition of amyloids—insoluble proteins that form due to the misfolding and aggregation of soluble proteins—outside of cells. Such depositions ...
Molecular & Computational biology
May 6, 2022
0
7
Researchers at Kanazawa University report in Proceedings of the National Academy of Sciences a responsive molecular system that, through chemical reactions, inverses its chirality before becoming racemic.
Materials Science
Mar 15, 2022
0
35
In a recent study published in the journal ACS Catalysis researchers from Kanazawa University describe novel scanning electrochemical cell microscopy measurements to determine sites of photoelectrochemical activity in titanium ...
Materials Science
Feb 21, 2022
0
136