Decoding how a protein on the move keeps cells healthy

Cells produce proteins like little factories. But if they make too much at the wrong times it can lead to diseases like cancer, so they control production with a process called RNA interference (RNAi). As of July 2021, several ...

For plant geneticists, some genes are double the trouble

When plant geneticists find a gene that improves crop yields, they want to try to insert that same change into other crops. But Cold Spring Harbor Laboratory Professor and HHMI Investigator Zachary Lippman cautions that ...

Stabilizing chromosomes to tackle tumors

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether. An enzyme called ...

Plants: RNA notes to self

How does a developing plant shoot know how, where, and when to grow? Dividing cells need to pass messages from one another to coordinate growth. In plants, important messages are packaged into RNA, which are sent from cell ...

Teaching an old chemical new tricks

They say you can't teach an old dog new tricks, but can you do new tricks with old chemical catalysts? Cold Spring Harbor Laboratory Professor John E. Moses and his team have paired a catalyst called "Barton's base" developed ...

Why roots don't grow in the shade

When a plant finds itself in too much shade, it redirects its resources to reach for light. Crop yield and root development stall as the plant focuses on growing taller, striving to rise above neighboring plants to access ...

Using math to calculate the path of cancer

Biologists at Cold Spring Harbor Laboratory (CSHL) are using a mathematical approach developed in CSHL Assistant Professor David McCandlish's lab to find solutions to a diverse set of biological problems. Originally created ...

Polymers 'click' together using green chemistry

SOF4 is a gas that was discovered over a hundred years ago but is rarely used because it is difficult to prepare and highly reactive. Now a collaboration of chemists including Cold Spring Harbor Laboratory (CSHL) Professor ...

How plants leave behind their parents' genomic baggage

Passing down a healthy genome is a critical part of creating viable offspring. But what happens when you have harmful modifications in your genome that you don't want to pass down? Baby plants have evolved a method to wipe ...

page 3 from 18