How cells control mitochondria

Errors in the metabolic processes of mitochondria are responsible for a variety of diseases such as Parkinson's and Alzheimer's. Scientists needed to find out just how the necessary building blocks are imported into the complex ...

A novel strategy for natural product biosynthesis

Microorganisms produce natural products, for example, as disease-causing virulence factors or as defense substances against predators and competitors. A team led by Dr. Robin Teufel and first author Ying Duan from the Institute ...

Molecular chaperones help with folding

Chaperones are molecular helpers that assist other proteins with folding. One such chaperone is the so-called heat shock protein 60 (Hsp60). This protein forms structures in mitochondria that resemble barrels in which folding ...

Stem cells regulate their fate by altering their stiffness

In adults, mesenchymal stems cells (MSCs) are primarily found in bone marrow and they play a vital role in repair of damaged organs. The transformation of a single MSC into complex tissue like cartilage and bone starts with ...

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