'Better detection' for Alzheimer's and cancers

August 26, 2013

A new chemical discovery will lead to better monitoring and treatment for cancers and degenerative diseases, according to latest research by scientists.

In a paper published today in ChemComm an international team of researchers from the Universities of Birmingham, Bath and the East China University of Science and Technology in Shanghai outline a new approach to detecting 'reactive oxygen' using fluorescence.

Reactive oxygen, which includes peroxides or , causes cell damage and degeneration in the body and its presence in high doses can be a sign of diseases such as Alzheimer's or cancers. The importance of reactive oxygen has led researchers to find new approaches for its quick and simple detection.

This latest research paves the way for new systems to detect changes in reactive which could help target interventions. Mapped using fluorescent imaging, the concentration of reactive oxygen in cells and tissue would light up which will help better understand and monitor disease development and intervention. Using fluorescence probes it will be possible to perform whole body imaging, making it is possible to monitor in situ tumour development in real-time.

Dr John Fossey from the School of Chemistry at the University of Birmingham said: 'This most recent project has taken the international CASE consortium in a different and exciting direction. Developing a new sensing model based on reactive oxygen has many useful applications in diagnosing and detecting disease.'

Professor Tony James from the University of Bath, commented: 'I am very excited by these new results which have pointed our research in an unexpected yet truly rewarding direction. This work uses 'simple' molecules which are capable of helping doctors understand and diagnose 'difficult'diseases.'

Explore further: Researchers create new class of fluorescent dyes to detect reactive oxygen species in vivo

Related Stories

A designer enzyme for alternative energy

June 21, 2013

(Phys.org) —Imagine pulling energy out of thin air. Yi Lu and his colleagues are on that path, in a quest to find alternatives to fossil fuels. The team has designed an enzyme that can harvest the energy of atmospheric ...

Light dynamics for cancer treatment

May 3, 2012

Research is delving into refinement of a revolutionary cancer treatment, photodynamic therapy (PDT). Using light, reactive oxygen and photosensitisers linked to specially designed antibodies, scientists are on the threshold ...

Enzyme may be a key to Alzheimer's-related cell death

October 6, 2009

(PhysOrg.com) -- A Purdue University researcher has discovered that the amount of an enzyme present in neurons can affect the mechanism thought to cause cell death in Alzheimer's disease patients and may have applications ...

Recommended for you

Scientists develop new theory of molecular evolution

October 23, 2017

Researchers from the University of Colorado Anschutz Medical Campus and the University College London have developed a new theory of molecular evolution, offering insights into how genes function, how the rates of evolutionary ...

Austrian researchers facilitate lipid data analysis

October 23, 2017

No lipids, no life. In all organisms, lipids form cell walls, store energy and release it when necessary, and play an important role in cell signalling. It has been proved that changes in the composition of lipids play a ...

Close up view of growing polymer chain show jump steps

October 20, 2017

(Phys.org)—A team of researchers at Cornell University has devised a means for watching as a polymer chain grows after application of a catalyst. In their paper published in the journal Science, the team explains how they ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.