How sex differences influence lung injury in mice

More than 2,500 genes exhibit significant sex differences in expression in mouse alveolar type II cells (AT2s), which are important for keeping the lungs functioning, potentially explaining sex biases in the prevalence and ...

Generating human-like neural networks via cellular reprogramming

A study published in the journal Stem Cells Reports reveals that a cellular reprogramming methodology allows the creation of neural networks that reproduce unique characteristics of human cells—different to those obtained ...

Stem cell-derived organoids mimic human parathyroid tissue

Patient-derived parathyroid organoids (PTOs) could pave the way for future physiology studies and drug-screening applications, as shown in a study published on October 27 in the journal Stem Cell Reports.

Making lab-grown brain organoids 'brainier'

By using stem cells to grow miniature brain-like organs in the lab, scientists have opened a new avenue for studies of neurological development, disease and therapies that can't be conducted in living people. But not all ...

Stem cell–derived liver cells give new clues to Ebola

Ebola virus causes serious infections in humans and in fatal cases, damage and dysfunction of the liver is often present, suggesting that the liver plays a decisive role in disease outcome. Although the liver can become directly ...

Sterile mice produce rat sperm

Researchers generated rat sperm cells inside sterile mice using a technique called blastocyst complementation. The advance appears August 4 in the journal Stem Cell Reports.

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