Organic Process Research & Development is a peer-reviewed scientific journal published since 1997 by the American Chemical Society. It is indexed in Chemical Abstracts Service, Scopus, EBSCOhost, British Library, and Web of Science. The current editor-in-chief is Trevor Laird.
The Vilsmeier reagent is necessary for producing a large range of pharmaceuticals, but its unstable nature and toxic precursor phosgene are challenges for its use. A new process that efficiently produces phosgene, the Vilsmeier ...
Analytical Chemistry
Sep 19, 2023
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11
Various chemical products, such as polymers and pharmaceutical intermediates, are currently synthesized with phosgene as their precursor or raw material. However, phosgene is highly toxic and this usage poses safety risks. ...
Analytical Chemistry
Nov 22, 2022
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17
The Food and Drug Administration wants the pharmaceutical industry to get away from making drugs using the traditional batch method and switch to a more modern process known as continuous manufacturing.
Engineering
Mar 7, 2019
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7
Scientists at Los Alamos National Laboratory and the U.S. Army Research Laboratory in Aberdeen, Maryland have developed a novel "melt-cast" explosive material that could be a suitable replacement for Trinitrotoluene, more ...
Materials Science
Jun 14, 2018
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51
Scientists from the U.S. Army Research Laboratory and the Lawrence Livermore National Laboratory found a solution to a significant challenge in making high-energy explosives. They safely improved the overall chemical yield ...
Materials Science
Jan 18, 2018
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9
A fungal form of meningitis leads to more than 600,000 deaths in Africa every year and is responsible for 20 percent of HIV/AIDS-related deaths globally, according to the U.S. Centers for Disease Control and Prevention. An ...
Materials Science
Feb 1, 2017
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6
Historically, pharmaceutical industries have relied on novel medications to meet profit targets; however in today's competitive markets, the huge expenditures associated with drug development now challenge this approach. ...
Materials Science
Aug 24, 2016
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8
Scientists are reporting development of a simple new procedure for removing almost 98 percent of an important impurity that can contaminate prescription drugs and potentially increase the risk for adverse health effects in ...
Biochemistry
Jun 20, 2012
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0
Scientists are reporting development of a new, higher-yield, two-step, less costly process that may ease supply problems and zigzagging prices for the raw material essential for making the mainstay drug for malaria. That ...
Biochemistry
May 23, 2012
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