Scientists decrypt the 'mechanical code' of DNA
A new study has deciphered the mechanical code of DNA to reveal previously unknown ways in which nature encodes biological information in DNA sequence.
A new study has deciphered the mechanical code of DNA to reveal previously unknown ways in which nature encodes biological information in DNA sequence.
Biotechnology
Dec 5, 2022
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110
Chronic pain is an extremely common condition that affects about 20% of the general population. Given the shortage of effective and non-addictive analgesics, new anti-pain drugs are eagerly awaited. Voltage-gated sodium channel ...
Molecular & Computational biology
Nov 28, 2022
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2
The mechanism by which fat-related molecules called lipids regulate pacemaker ion channel proteins, which help control the heart rhythm, has been revealed in a study from researchers at Weill Cornell Medicine.
Molecular & Computational biology
Nov 9, 2022
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33
In a living being, proteins make up roughly everything: from the molecular machines running every cell's metabolism, to the tip of your hair. Encoded in the DNA, a protein may be represented as a thread of hundreds of individual ...
Biotechnology
Nov 8, 2022
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49
A new imaging technique captures the structure of the human genome at unprecedented resolution, revealing how individual genes fold at the nucleosome level—the fundamental units constituting the genome's three-dimensional ...
Cell & Microbiology
Oct 13, 2022
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350
The hepatitis B virus (HBV) is responsible for one of the most serious and common infectious diseases. Transmitted through biological fluids, it attacks the liver cells. The chronic form of the disease can lead to serious ...
Cell & Microbiology
Oct 4, 2022
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8
In a new study, researchers from the Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This insight, they say, reveals ...
Cell & Microbiology
Sep 12, 2022
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142
A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19. The discovery could lead to the design of critically ...
Molecular & Computational biology
Sep 8, 2022
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65
Metabolic diseases, including diabetes, fatty liver, and obesity, have become a major "killer" affecting human health. Studies have shown that some orphan receptors could be targets for the treatment of these diseases. GPR119, ...
Biochemistry
Aug 18, 2022
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21
The amount of salt and water in our cells and their pH is strictly controlled for cell survival. To maintain the necessary balance, special proteins perform the essential role of exchanging protons (hydrogen ions, or H+) ...
Cell & Microbiology
May 30, 2022
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71