DNA repeats—the genome's dark matter

Expansions of DNA repeats are very hard to analyze. A method developed by researchers at the Max Planck Institute for Molecular Genetics in Berlin allows for a detailed look at these previously inaccessible regions of the ...

Researchers develop new tools for precise large DNA insertions

Gao Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) has developed a new genome editing technology that achieves efficient and precise targeted insertion of ...

AI and single-cell genomics: New software predicts cell fate

Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions—but they do this with static snapshots only rather than time-lapse films. This limitation makes it difficult to ...

New tool offers ways to improve CRISPR gene-editing method

The ability to edit the genome by altering the DNA sequence inside a living cell is powerful for research and holds enormous promise for the treatment of diseases. However, existing genome editing technologies frequently ...

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