DNA repeats—the genome's dark matter

Expansions of DNA repeats are very hard to analyze. A method developed by researchers at the Max Planck Institute for Molecular Genetics in Berlin allows for a detailed look at these previously inaccessible regions of the ...

AI and single-cell genomics: New software predicts cell fate

Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions—but they do this with static snapshots only rather than time-lapse films. This limitation makes it difficult to ...

Researchers create new spatial omics method

Researchers at Uppsala University, Stockholm University and KTH Royal Institute of Technology have managed to create a new spatial omics method. By combining two complex techniques that are usually used separately—mass ...

New tool offers ways to improve CRISPR gene-editing method

The ability to edit the genome by altering the DNA sequence inside a living cell is powerful for research and holds enormous promise for the treatment of diseases. However, existing genome editing technologies frequently ...

Improving the accuracy of long-read genome sequencing

A team of researchers from institutions in the U.S., Germany and China has developed a way to improve the accuracy of long-read genome sequencing. In their paper published in the journal Nature Biotechnology, the group outlines ...

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