New method shows role of elusive RNA in muscle regeneration

In recent years, scientists who study gene expression in cells have used a method that essentially pins a tail on RNA and tracks their whereabouts. However, certain types of RNA evade the process. Now, a Cornell team has ...

New way to target 'undruggable' molecules involved in cancer

For decades, cancer researchers have longed for a way to target a set of proteins called transcription factors. While we've long known that tumors use these proteins to grow out of control, their unique configurations meant ...

Even good gene edits can go bad

A Rice University lab is leading the effort to reveal potential threats to the efficacy and safety of therapies based on CRISPR-Cas9, the Nobel Prize-winning gene editing technique, even when it appears to be working as planned.

New CRISPR-Cas approach permits more precise DNA cleavage

A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies. The recent innovation, which is published in Nature ...

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