An FDA-approved drug for hepatitis C can increase bacterial sensitivity to antibiotics and reduce the likelihood of antibiotic resistance, according to a new study led by New York University researchers published in Cell ...
Biochemistry
Nov 23, 2021
0
97
A study out of the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University has resulted in the discovery of a promising new antimalarial compound.
Biochemistry
Oct 27, 2021
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76
Recently, TANG Gongli's group from the Shanghai Institute of Organic Chemistry and University of Chinese Academy of Sciences reported the biosynthetic pathway of mechercharmycin A (MCM-A), a marine natural product belonging ...
Biochemistry
Sep 6, 2021
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14
Mutant DNA sequences inside cellular mitochondria can be eliminated using a bespoke chemical compound. The approach, developed by scientists at Kyoto University's Institute for Integrated Cell-Material Science (iCeMS) in ...
Cell & Microbiology
Aug 27, 2021
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197
Every year, more than 200 million people are infected with malaria, and nearly 500,000 die from the disease. Existing drugs can treat the infection, but the parasite that causes the disease has evolved resistance to many ...
Biochemistry
Aug 10, 2021
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312
In the latest of ongoing efforts to expand technologies for modifying genes and their expression, researchers in the lab of Neville Sanjana at New York University (NYU) and the New York Genome Center (NYGC) have developed ...
Cell & Microbiology
Aug 3, 2021
0
247
When Alexander Flemming discovered a mold on a culture plate overgrown with bacteria in 1928, he did not expect to find one of the most widely used active substances: penicillin. Accidental discoveries and the identification ...
Biochemistry
Jul 22, 2021
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286
Researchers have developed a more efficient platform for studying proteins that play a key role in regulating gene expression. The approach uses engineered yeast cells to produce enzyme and histone proteins, conduct biochemical ...
Biochemistry
Jul 1, 2021
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16
Polypharmacology—the ability of a drug to affect more than one protein—should be studied early in the drug discovery pathway, and constantly monitored as the chemical structure is optimized in the design of the clinical ...
Biochemistry
Jun 2, 2021
0
6
Researchers from Ben-Gurion University (BGU), together with American and German colleagues, have developed new "molecular tweezers" to combat antibiotic-resistant bacteria. Their recently announced findings were published ...
Biotechnology
May 10, 2021
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123
