Nanovesicles from cells for biomedical applications
National University of Singapore scientists have fabricated nano-sized vesicles from cells via a cell shearing approach that can be used for various biomedical applications.
Surfactants, micelles, and vesicles constitute a class of self-assembled soft-matter physical systems arising from amphiphilic molecules in solution. Above the critical micelle concentration, surfactants spontaneously form micelles, typically spherical or anisotropic aggregates with hydrophobic cores and hydrophilic coronas, governed by minimization of interfacial free energy and packing constraints. At higher concentrations or appropriate conditions (e.g., temperature, ionic strength, tail architecture), these assemblies can transition into bilayer-based vesicles, closed shell structures encapsulating aqueous volumes and exhibiting bending elasticity, membrane tension, and permeability properties. Collectively, these systems serve as model platforms for studying interfacial thermodynamics, mesoscale organization, and transport phenomena in complex fluids.
National University of Singapore scientists have fabricated nano-sized vesicles from cells via a cell shearing approach that can be used for various biomedical applications.
Bio & Medicine
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