Immunology is the scientific discipline that investigates the molecular, cellular, and systemic mechanisms underlying immune recognition, regulation, and effector function in vertebrates and other organisms. It encompasses the study of innate and adaptive immune responses, including antigen processing and presentation, clonal selection, tolerance, immune memory, and the cytokine networks that orchestrate these processes. Immunology also examines the pathophysiology of immune-mediated diseases such as autoimmunity, allergy, immunodeficiencies, and transplant rejection, and underpins the rational design of vaccines, monoclonal antibodies, immunotherapies, and diagnostic assays through quantitative, genetic, and systems-level approaches.
Although the mRNA COVID-19 vaccines from Pfizer-BioNTech and Moderna are safe and effective at preventing severe illness in adults and children, including immunocompromised individuals, researchers have noticed that these ...
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Apr 3, 2023
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Newly developed mRNA vaccines against Zika virus and HIV-1 produced strong antibody responses that transferred from pregnant rabbits to their offspring, researchers report in the journal Molecular Therapy. As noted by the ...
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Mar 24, 2023
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The human body is made up of thousands of tiny lymphatic vessels that ferry white blood cells and proteins around the body, like a superhighway of the immune system. It's remarkably efficient, but if damaged from injury or ...
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Mar 20, 2023
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COVID is not yet under control. Despite a bevy of vaccines, monoclonal antibodies, and antivirals, the virus continues to mutate and elude us. One solution that scientists have been exploring since the early days of the pandemic ...
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Mar 14, 2023
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Macrophages are highly specialized cells of the immune system that help the body detect and fight deadly pathogens. In particular, M1-like macrophages detect and destroy tumor cells, and release protective chemokines such ...
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Mar 7, 2023
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A new way to significantly increase the potency of almost any vaccine has been developed by researchers from the International Institute for Nanotechnology (IIN) at Northwestern University. The scientists used chemistry and ...
Bio & Medicine
Jan 31, 2023
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The nanomaterial graphene oxide—which is used in everything from electronics to sensors for biomolecules—can indirectly affect the immune system via the gut microbiome, as shown in a new study on zebrafish by researchers ...
Bio & Medicine
Dec 12, 2022
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Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer. However, immune checkpoint inhibition therapy is only effective in 20%–30% ...
Bio & Medicine
Oct 31, 2022
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An important component of the vaccines protecting people against SARS-CoV-2 virus and its variants are lipid nanoparticles, or LNPs. These circular particles carry therapeutic mRNA payloads, the snippets of genetic material ...
Bio & Medicine
Sep 23, 2022
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Scientists in the department of Advanced Organ Bioengineering and Therapeutics (Faculty of S&T, TechMed Centre) recently published a novel cancer immune therapy in the scientific journal Nature Communications. In their research, ...
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Aug 11, 2022
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