Immunology is the scientific discipline that investigates the molecular, cellular, and systemic mechanisms underlying immune recognition, regulation, and effector function in vertebrates and other organisms. It encompasses the study of innate and adaptive immune responses, including antigen processing and presentation, clonal selection, tolerance, immune memory, and the cytokine networks that orchestrate these processes. Immunology also examines the pathophysiology of immune-mediated diseases such as autoimmunity, allergy, immunodeficiencies, and transplant rejection, and underpins the rational design of vaccines, monoclonal antibodies, immunotherapies, and diagnostic assays through quantitative, genetic, and systems-level approaches.
Some COVID-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy. ...
Bio & Medicine
Dec 11, 2023
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A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target ...
Bio & Medicine
Dec 8, 2023
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UCLA researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.
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Oct 11, 2023
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Macrophages are cells vital to the immune system and could possibly inform cell-based therapies for a variety of medical conditions. However, realizing the full potential of macrophage therapies relies on being able to see ...
Bio & Medicine
Sep 21, 2023
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A new study highlights the potential of artificial DNA structures that, when fitted with antibodies, instruct the immune system to specifically target cancerous cells.
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Aug 18, 2023
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Excessive activation of inflammasomes is associated with various diseases, including gout, Alzheimer's disease, atherosclerosis, and type 2 diabetes. Given the pivotal role of macrophages in both inflammasome activation and ...
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Jul 24, 2023
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Over the past decade, researchers have sought more effective and enduring cancer treatments. Among the wide variety of immunotherapies, Stimulator of Interfron Genes activation (STING agonism) has emerged as a particularly ...
Bio & Medicine
Jul 13, 2023
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In a recent study from the Wilmer Eye Institute, researchers say they found that using a nanoparticle to target immune cells in the eyes of zebrafish enhanced neuron regeneration rates after injury. This research expands ...
Bio & Medicine
Jun 22, 2023
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Nanoparticles consisting of a designer protein that counteract an overreaction of the immune system, while simultaneously boosting that system. This invention offers possibilities for the treatment of sepsis, a condition ...
Bio & Medicine
Jun 9, 2023
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The fact that our immune systems capture and destroy nanoparticles and the drugs they carry has been a problem in the field of nanomedicine for some time. But, in the fight against cancer, researchers are now attempting to ...
Bio & Medicine
Jun 8, 2023
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