Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.
During animal cell division, a highly synchronized and tightly regulated dance of chromosomes takes place, ensuring the chromosomes split correctly into the two cells. Spindle fibers—complex machinery responsible for choreographing ...
Cell & Microbiology
May 27, 2026
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Smaller plastic particles have more effects on neurons, the key information processing cells of the brain, new research from the University of Eastern Finland shows. In the study, neuronal cells were exposed to polystyrene ...
Bio & Medicine
May 27, 2026
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A study by researchers at Duke University School of Medicine identifies a new way that G protein–coupled receptors (GPCRs)—targets of roughly one-third of FDA-approved drugs—control signaling in cells. The paper is published ...
Molecular & Computational biology
May 27, 2026
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In a study published in ACS Nano, researchers from National Taiwan University report a new expansion microscopy strategy termed high-fold homogeneous expansion microscopy (hiHomoExM), capable of achieving approximately 8–9× ...
Bio & Medicine
May 26, 2026
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21
A new study led by the Universidad Carlos III de Madrid (UC3M) describes the mechano-chemical mechanism by which the acidity of the cellular environment destabilizes microtubules, the "avenues" that organize internal cellular ...
Cell & Microbiology
May 26, 2026
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University of Cincinnati structural biologists are the first in the world to visualize a key cell protein as part of newly published research from the College of Medicine. The Seegar Lab has become the first to visualize ...
Cell & Microbiology
May 25, 2026
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The buildup of a protein called 𝛂-synuclein (ASN) into toxic clumps is a hallmark of synucleinopathies, a group of neurodegenerative diseases that includes Parkinson's and multiple system atrophy (MSA). These aggregates are ...
Bio & Medicine
May 24, 2026
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145
In a cramped, windowless room on the University of California, Berkeley, campus, two bespoke microscopes—each a Swiss Army knife for high-resolution imaging—operate around the clock gathering data that will help train a game-changing ...
Biotechnology
May 22, 2026
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Northwestern Medicine scientists have developed a new experimental method to analyze conformational fluctuations in protein domains on a uniquely large scale, which may improve data-driven modeling, biology and protein engineering, ...
Molecular & Computational biology
May 21, 2026
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11
Living systems such as cells rely on membrane pores and channels to transport molecules, exchange signals, and organize biochemical reactions. These functions emerge from dynamic interactions between molecular components. ...
Bio & Medicine
May 21, 2026
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